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EuroSIDA Study Finds a Signal of Kidney Toxicity With Tenofovir or Atazanavir

The kidneys are a target of HIV infection. Long-term infection causes inflammation, which slowly degrades these organs.

The EuroSIDA dataset contains health-related information on almost 17,000 HIV-positive people from 35 countries. EuroSIDA can pro...

HIV and Inflammation: A New Threat Img

HIV and Inflammation: A New Threat

Introduction What Is Inflammation? Inflammatory Markers and Mortality Aging Before Your Time? Conclusion


Traditionally, it was thought that the natural course of HIV included a period of latency -- a time when the virus was i...

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Tenofovir and the Kidneys

The anti-HIV drug tenofovir (Viread, and in Atripla and Truvada) is an effective part of combination therapy for HIV.

The kidneys process tenofovir and there have been rare cases of tenofovir users developing serious kidney dysfunction. To investiga...

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Kidney Transplant Survival Can Be Long-Term for People With HIV

A Johns Hopkins study finds that HIV-positive kidney transplant recipients could have the same one-year survival rates for themselves and their donor organs as those without HIV, provided certain risk factors for transplant failure are recognized and...

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Renal Insufficiency Among HIV-Infected Patients in the SUN Study

Turner Overton, M.D.

Hi. This is Turner Overton from Washington University in St. Louis. I'm in front of our poster, "Prevalence and Predictors of Renal Insufficiency Among HIV-Infected Patients."1 This is part of the SUN cohort, which is a CDC [U....

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Renal Complications of HIV/AIDS

Introduction Assessing Kidney Function Types of Kidney Disease Complications of Decreased Kidney Function The Impacts of Kidney Disease on Medications and of Medications on Kidney Disease Conclusion Selected Sources



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The Effect of Tenofovir and Other Antiretroviral Therapy on Renal Tubular Cells in Vitro

There remains considerable argument over the role, if any, tenofovir (TDF, Viread) use plays in observed renal dysfunction during antiretroviral therapy. Long-term clinical studies such as GS9031 have not reported declines in glomerular filtration ra...

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Link Between Tenofovir and Renal Toxicity Remains Tenuous, but Monitoring Is Warranted

One of the most popular and widely prescribed antiretroviral medications is tenofovir (TDF, Viread). Overall, the drug has few side effects or toxicities -- a fact that has formed the basis of recommendations for its use in multiple HIV treatment gui...

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Tenofovir Proves Safe for Kidneys After Three Years of Use

Treatment with antiretroviral agents is often fraught with a host of adverse effects. An emerging topic of great concern within the field of anti-HIV treatment relates to the fact that certain nucleoside/nucleotide reverse transcriptase inhibitors (N...

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No Major Renal Problems With Tenofovir Were Identified in the Naive Population Evaluated in the GS 903 Study

With only two years of collected data, the GS 903 study from Gilead Sciences has already proved that the combination of tenofovir DF (TDF, Viread), 3TC (lamivudine, Epivir) and efavirenz (EFV, Sustiva) is very effective in controlling viral replicati...