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Kidney

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Serious Kidney Problems Are Rare With PrEP, but Increase With Older Age and Better Adherence Img

Serious Kidney Problems Are Rare With PrEP, but Increase With Older Age and Better Adherence

Three studies offer reassuring news that adverse kidney changes that accompany Truvada use for PrEP are rarely serious and universally reverse after stopping the medication, but also that older people and those with the best adherence might need to b...

How PrEP Changes Kidney Function Img

How PrEP Changes Kidney Function

Research presented at CROI 2016 shows that Truvada PrEP is safe for most people, but impaired kidney function -- usually mild or moderate -- may occur in a small proportion of people on PrEP, especially if they have other risk factors.

Kidney Risk Climbs With Increasing Time on Tenofovir, Atazanavir or Lopinavir Img

Kidney Risk Climbs With Increasing Time on Tenofovir, Atazanavir or Lopinavir

In people with initially normal kidney function, each additional year taking tenofovir disoproxil fumarate (TDF, Viread), ritonavir (Norvir)-boosted atazanavir (Reyataz) or lopinavir/ritonavir (Kaletra) raised the risk of chronic kidney disease (CKD)...

Tenofovir Alafenamide (TAF) in People With Kidney Dysfunction Img

Tenofovir Alafenamide (TAF) in People With Kidney Dysfunction

In general, tenofovir alafenamide (TAF) is safe, with improvements in bone and kidney health over tenofovir disoproxil fumarate (TDF). However, those with severe kidney disease may not see improvements in kidney health, according to a recent study....

Single-Tablet HIV Regimen Containing Tenofovir Alafenamide Improves Bone and Kidney Safety Img

Single-Tablet HIV Regimen Containing Tenofovir Alafenamide Improves Bone and Kidney Safety

A new single-tablet HIV regimen containing tenofovir alafenamide (TAF) offered better bone and kidney safety, according to a study presented at ICAAC/ICC 2015.

Tenofovir Alafenamide (TAF) Gentler on the Bones and Kidneys Img

Tenofovir Alafenamide (TAF) Gentler on the Bones and Kidneys

The new formulation of tenofovir, tenofovir alafenamide (TAF), was associated with less harm to bones and kidneys than the older formulation, tenofovir disoproxil fumarate (TDF, Viread).

Long-Term Tenofovir Use Associated With Higher Rates of Kidney Problems Img

Long-Term Tenofovir Use Associated With Higher Rates of Kidney Problems

Renal dysfunction was more likely in patients who had taken tenofovir (Truvada, TDF) longer, were older, or also had diabetes or hypertension, according to a study presented at IDWeek 2014.

Cobicistat Safe for HIV-Positive Patients With Mild to Moderate Renal Impairment Img

Cobicistat Safe for HIV-Positive Patients With Mild to Moderate Renal Impairment

Study finds cobicistat-containing regimens are effective and well-tolerated by HIV-infected patients with mild to moderate renal impairment.

Truvada as PrEP Does Not Cause Kidney Damage, Study Suggests Img

Truvada as PrEP Does Not Cause Kidney Damage, Study Suggests

Taking Truvada (tenofovir/emtricitabine) as pre-exposure prophylaxis (PrEP) has little effect on kidney function, according to a new study.

Increased Risk for Dialysis Found With HIV Infection Img

Increased Risk for Dialysis Found With HIV Infection

Someone diagnosed with HIV nowadays -- who is quickly put on ART -- can live a near-normal lifespan, but many organs, like the kidneys, are affected by HIV and need monitoring.