There are two main philosophies on establishing an HIV cure. One is the traditional "sterilizing cure," which would eradicate all replication-competent virus in the body and eliminate the HIV reservoir. The second is a "functional cure," or what's now commonly called "HIV remission," which, without antiretroviral therapy, would induce permanent or sustained viral suppression to levels that would prevent immunodeficiency and transmission. Currently, the more achievable goal would be HIV remission.
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