Two-thirds of women highly likely to be viremic were unstably housed, a longitudinal study published in JAMA Network Open found.
Researchers analyzed 23 years of data on 1989 people enrolled in the Women’s Interagency HIV Study (WIHS) in Chicago, New York (Brooklyn and Bronx Counties), San Francisco, and Washington, D.C. Modeling identified three trajectories: low (29% of participants), intermediate (39%), or high (32%) probability of viremia (defined as having a viral load > 200 copies/mL).
The proportion of viremic women dropped in all groups over time, partly due to changes in treatment guidelines and the recent availability of more effective regimens. In the most recent time period, spanning 2015 to 2017, 90% of participants in the low-probability group were virally suppressed, compared to 83% in the intermediate-probability group, and 35% in the high-probability group.
Participants in the high-probability group were more likely to be unstably housed (66% of the 637 women in that group), suffer from depression, and report current drug and alcohol use compared to women in the other two groups.
Study authors called for further research that includes other geographic locations, as well as identification of replicable programs to improve sustained viral suppression rates.