There are different drivers for and against researching and developing nanomedicines, but the pros outweigh the cons, Owen asserted. On the downside, there can be issues with insolubility of active pharmaceutical ingredients, and the difficulty and cost of formulation during development can be high. However, the pros that nanomedicines could offer include a modified delivery profile, a solution to fed/fasted variability, an improvement in patient adherence, a reduction in pill burden and decreased adverse drug reactions.
Pre-clinical research has shown that nano-formulations have greater potency at lower dosage levels than conventional formulations. Furthermore, with intramuscular or intravenous delivery, there could be a sustained release of the drug and better targeting of the virus.