Phase 2a results were announced in a study to understand the safety and to determine an effective dose of the combination of odalasvir, AL-335 with and without simeprevir to treat HCV genotype 1 treatment-naive patients.
Effectiveness of Sofosbuvir, Ledipasvir/Sofosbuvir, or Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir Regimens for Treatment of Patients With Hepatitis C in the Veterans Affairs National Health Care System
"The Veterans Affairs Healthcare system is a perfect place to test for 'real world' results," Alan Franciscus writes. "How do the direct-acting antiviral drugs work in a 'real world' setting as opposed to clinical trials?"
An important study was recently published in Lancet Gastroenterology & Hepatology holds the promise of changing the way that people with hepatitis C are treated.
Consequences of Inaccurate Hepatitis C Virus Genotyping on the Costs of Prescription of Direct Antiviral Agents in an Italian District
Researchers conducted a study to analyze commercial hepatitis C genotype/subtype assays to understand the cost-effectiveness of potential errors in the assays.
"Not only is nothing private on the internet, it is forever," Lucinda K. Porter, R.N., writes. "Information cannot be erased from the web. So, if you don't want people to know about your having hepatitis C, don't tell anyone."
Type of antiretroviral regimen did not affect sustained virologic response 12 weeks after therapy stopped (SVR12) in a 12-week trial of daclatasvir/sofosbuvir (DCV/SOF).
Among patients coinfected with hepatitis C (HCV) and HIV, sustained virologic response 12 weeks after HCV therapy ended (SVR12) was significantly higher with simeprevir (SMV) and sofosbuvir (SOF, Sovaldi) plus ribavirin (RBV) than with SOF/RBV in a t...
"Health disparities can act a bit like compound interest," Matthew Zielske writes. "Each new health or socioeconomic concern that arises will be added to the existing pool of problems which will lead to further tangling the knot."
One third of gay or bisexual men infected with HIV and hepatitis C virus had detectable HCV in their semen.
Mark Mascolini reports on a new study comparing statin indications in male veterans with HIV, HCV or both with three sets of cholesterol guidelines and examining why almost one-third of statin-eligible veterans were not getting the drugs.