What's New in the U.S. HIV Clinical Guidelines

We walk you through the most recent updates to official guidelines issued by the U.S. Department of Health and Human Services on the treatment and care of people living with HIV.

By Stephen Hicks


Researchers Recommend Screening All People With HIV for Elevated Liver Function Values

Authors of a literature review note the high prevalence of liver disease among people with HIV and recommend a step-by-step approach to management.

By Barbara Jungwirth

Large French Study Examines Neuropsychiatric Side Effects With Integrase Inhibitors

This will likely become the landmark study about the overall rate of neuropsychiatric side effects with this class of medicines over the next several years.

By Sean R. Hosein for Canadian AIDS Treatment Information Exchange

Researchers Crave More Data on HIV Care Continuum Programs for Recently Incarcerated People

Sixteen years after the success of Project START for HIV risk reduction, we still don't know what works best for helping people with HIV stay in care after prison.

By Sony Salzman

Native Americans Have HIV Treatment Adherence Rates on Par With Other Groups

Despite rising HIV rates and structural barriers to accessing care, American Indians and Alaska Natives do not have worse clinical outcomes when they're in care.

By Sony Salzman

De-Simplifying Single-Tablet Regimens for HIV Treatment

A Canadian study of this cost-saving approach found high acceptance of de-simplification among people already on a single-tablet regimen, and even higher rates among people who were just initiating single-tablet treatment.

By Sean R. Hosein for Canadian AIDS Treatment Information Exchange

Why Nurses Should Take the HIV Self-Test

People newly diagnosed with HIV must be able to access treatment and support, which could be improved if guided by people who have been taken the test themselves, researchers found.

By Amanda Lee and Mark Hayter for The Conversation

PositiveLinks: Mobile Intervention for People With HIV

Study results of an intervention that includes a custom smartphone app tailored to the needs and preferences of a rural population of people with HIV living in the southern U.S.

By Canadian AIDS Treatment Information Exchange

Doravirine Sets a New Standard for NNRTIs -- but What Role in HIV Treatment Today?

"Since this appears to be a 'best in class' drug, doravirine has enough advantages that it is a useful advance in HIV therapy, if not a transformational one," writes Paul Sax, M.D.

By Paul E. Sax, M.D. for NEJM Journal Watch

FDA Approves Doravirine (Pifeltro) and New FDC With TDF/3TC (Delstrigo) in the U.S.

On Aug. 30, 2018, the U.S. FDA approved doravirine as a separate formulation for use with ART and in a fixed-dose combination with generic tenofovir DF and lamivudine (3TC).

By Simon Collins for HIV i-Base

More People With HIV Virally Suppressed on Doravirine Than Darunavir at 96 Weeks, Study Shows

After 96 weeks, more people achieved viral suppression on a doravirine-based antiretroviral drug regimen compared with a darunavir (Prezista)-based one, according to data presented at the recent 22nd International AIDS Conference.

By Barbara Jungwirth