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Zidovudine (AZT, Retrovir)

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Botswana

HAART More Effective Than AZT Monotherapy in the Botswana PMTCT Programme

There are limited data from programmes in resource-limited settings describing the effectiveness of HAART compared to AZT monotherapy for PMTCT.

Scott Dryden-Peterson and colleagues from Botswana showed findings from a prospective, observational stu...

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News

GlaxoSmithKline Announces New Program to Provide Financial Assistance for Eligible HIV Patients in the U.S.

Research Triangle Park -- GlaxoSmithKline [NYSE: GSK] announced today the launch of a new Patient Savings Card designed to help eligible patients improve compliance with their HIV regimens by reducing their out-of-pocket expenses for GSK HIV medica...

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News

FDA Approves Four Generic Forms of Zidovudine for U.S. Sales After Retrovir's Patent Expires

FDA on Monday announced it has granted approval for four forms of the generic antiretroviral drug zidovudine to be sold in the U.S., after GlaxoSmithKline's patent on the drug -- sold under the brand name Retrovir -- expired on Saturday, Dow Jones re...

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Approval of Generic Zidovudine

On September 19, 2005, FDA approved several generic formulations of Zidovudine for the U.S. market.

Previously, the products had been only tentatively approved and were not available in the United States because patent or market exclusivity blocked ...

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News

GlaxoSmithKline's Patent on Retrovir Expires; Generic Versions of AZT Expected to Be Available Soon

The patent on azidothymidine, or AZT -- the main ingredient in GlaxoSmithKline's antiretroviral drug Retrovir -- expired on Saturday, paving the way for lower-cost generic versions to be made available for millions of HIV-positive people in developin...

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Blood Disorders

Incidence of Zidovudine-Associated Anemia May Be Lower Than Initially Thought -- Particularly With Fixed-Dose Combinations

In the beginning, there was zidovudine (AZT, Retrovir). As the first antiretroviral drug approved for the treatment of HIV, its benefits during the early years of the epidemic were incalculable. However, zidovudine's use also had at least one downsid...

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News

WHO Removes Cipla's Lamivudine, Zidovudine Generics From Approved Drug List

A World Health Organization official on Tuesday said that the agency has removed two generic antiretroviral drugs produced by Indian generic drug manufacturer Cipla from its list of approved HIV treatments, the New York Times reports. Dr. Lembit Rago...

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Mother-to-Child Transmission: How Will AZT and Nevirapine Use for MTCT Affect Future Treatment?

Two studies in the November 1, 2003 edition of the Journal of Acquired Immune Deficiency Syndromes [JAIDS] address the issue of drug resistance in women taking antiretroviral prophylaxis to prevent mother-to-child transmission [MTCT] of HIV. On...

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A Comparison of AZT/3TC vs. d4T/ddI, Plus Efavirenz, Nevirapine or Indinavir/Ritonavir

Controversy still exists regarding which is the best antiretroviral therapy (ART) to start with. We all agree that the regimen must be potent, safe, well tolerated, convenient for the individual, and must demonstrate both efficacy and durability.

An...

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Nevirapine Reduced Mother-to-Child Transmission Better Than AZT -- At 70 Times Less Cost

A single dose of nevirapine given to an HIV-positive woman during labor, and a single dose given to her infant soon after birth, reduced HIV transmission 41% better than AZT when the infants were age 18 months, in a study conducted by researchers at ...