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Saquinavir (Invirase)

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Roche to Discontinue Supply of Saquinavir (Invirase) 200 mg Capsule for HIV Img
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Roche to Discontinue Supply of Saquinavir (Invirase) 200 mg Capsule for HIV

As the demand for this protease inhibitor has decreased significantly over the past 20 years, the manufacturer of saquinavir has announced that it will discontinue the manufacture and supply of the 200 mg capsule version of the drug.

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Roche to Discontinue Production of Nelfinavir and Saquinavir 200-mg Hard Capsules

Roche Laboratories have announced that they intend to discontinue the production of nelfinavir powder and tablets globally when the European patent ends on 23 January 2013.

The decision has been made due to the extremely low use together with the av...

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FDA Drug Safety Communication: Invirase (Saquinavir) Labels Now Contain Updated Risk Information on Abnormal Heart Rhythms

The U.S. Food and Drug Administration issued a notice about the addition of new heart risk information to the drug label for Invirase (saquinavir). The information describes a potential change in the electrical activity of the heart when Invirase is ...

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New FDA Warning on HIV Drugs Invirase and Norvir

On Tuesday, the Food and Drug Administration issued an announcement about an ongoing safety review of the combination of HIV drugs Invirase (saquinavir) and Norvir (ritonavir). In a low dose, Norvir is used to boost the level of Invirase in the body....

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Ongoing Safety Review of Invirase (Saquinavir) and Possible Association With Abnormal Heart Rhythms

The Food and Drug Administration (FDA) is reviewing clinical trial data about a potentially serious effect on the heart from the use of Invirase (saquinavir) in combination with Norvir (ritonavir). The data suggest that together the two drugs may aff...

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Tuberculosis

Drug Interaction Warning: Saquinavir/Ritonavir and Rifampin (Rifampicin, Rifadin, Rimactane, Rofact)

Roche Laboratories Inc. has issued a "Dear Health Care Provider" letter (PDF) to communicate an important drug interaction warning for saquinavir/ritonavir, used as part of combination therapy for treatment of HIV infection:

Drug-induced hepatitis w...

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New 500-mg Tablet Formulation of Invirase (Saquinavir) Approved

FDA approved, on December 17, 2004, a new 500-mg tablet formulation of the HIV protease inhibitor, INVIRASE (saquinavir mesylate). The dosage and administration for INVIRASE in adults (over the age of 16 years) is 1,000 mg twice a day (taken as eithe...