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Ritonavir (Norvir)

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FDA Approves New Oral Powder Formulation of Ritonavir (Norvir, RTV) Img
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FDA Approves New Oral Powder Formulation of Ritonavir (Norvir, RTV)

This approval provides for the use of ritonavir (Norvir) oral powder in combination with other antiretroviral agents for the treatment of pediatric patients with HIV-1 infection.

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People Who Use Drugs

Case Reports of Complications From Ketamine Use in Two MSM on Ritonavir-Based Combinations

Zhou and colleagues from Brighton and Sussex Hospitals presented a poster detailing two cases of bile duct and liver complications related to recreational use of ketamine.

Both patients had regularly used ketamine for 12 months and were taking riton...

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Intranasal and Topical Corticosteroids and Risk of Cushing's Symptoms in HIV Patients on Ritonavir-Based Combinations

Although iatrogenic Cushing's syndrome has previously been reported as a complication from the drug-drug interaction between ritonavir and corticosteroids (we included two cases in HTB last year), two posters at BHIVA this year highlighted low awaren...

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African-Americans

Warfarin and ARVs: Impact of African-American Race and Ritonavir

The commonly prescribed anticoagulant warfarin is highly susceptible to interactions with antiretroviral mediated through CYP 2C9, 2C19, and/or 3A4 pathways, although data are limited.

This retrospective, case‐control (1:2) study compared the warfar...

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News

Norvir (Ritonavir) Labeling Revised to Include New Warnings on Side Effects, Drug Interactions

On December 7, 2011, the Food and Drug Administration approved the following revisions to the Norvir (ritonavir) tablets, capsules and oral solution product labeling:

The Contraindications section was updated to include toxic epidermal necrolysis (T...

Top 10 HIV/AIDS-Related Clinical Developments of 2011 Img
Women

Top 10 HIV/AIDS-Related Clinical Developments of 2011

David Wohl, M.D., takes an in-depth look at this year's most critical HIV-related studies, and explains how each one may change how we prevent and treat HIV in 2012 and beyond. (Fair warning: This article can get pretty technical, but each story has ...

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Dose Optimisation: 50 mg Ritonavir-Boosting, 3TC Dosing and Raltegravir Once-Daily

The issue of dose optimisation is important for several reasons, ranging from finding the right dose for an individual patient that achieves the highest probability of therapeutic success with the lowest risk of adverse events, to as a strategy to de...

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News

U.S. Jury Rejects Glaxo Antitrust Claim vs. Abbott

In Oakland, Calif., on Wednesday, a 10-member federal jury rejected GlaxoSmithKline's (GSK) antitrust claim that Abbott Laboratories had quadrupled the price of its HIV drug Norvir in order to preserve the sales growth of its HIV drug Kaletra.

Norvi...

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News

New FDA Warning on HIV Drugs Invirase and Norvir

On Tuesday, the Food and Drug Administration issued an announcement about an ongoing safety review of the combination of HIV drugs Invirase (saquinavir) and Norvir (ritonavir). In a low dose, Norvir is used to boost the level of Invirase in the body....

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News

FDA Approves New Tablet Formulation of Norvir (Ritonavir)

On February 10, 2010, FDA approved Norvir (ritonavir) 100 mg Tablets. These tablets do not require refrigeration.

Summarized below are highlights from the new Norvir Tablet package insert.

Unlike the capsule formulation, Norvir tablets must be take...