Raltegravir (Isentress)

IAS (International AIDS Society) Conference

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Cross-Resistance Between Integrase Inhibitors

HIV integrase inhibitors represent a new class of antiretroviral drugs that target a crucial post-transcriptional event in the life cycle of HIV. There is considerable excitement about the potential of this new class of antiretroviral agents to revol...

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Faster Viral Decay With Raltegravir

The lead agent in the integrase inhibitor drug class, raltegravir (RAL, MK-0518) has demonstrated potent antiretroviral activity in phase 2 and 3 clinical trials conducted in both treatment-naive1 and treatment-experienced individuals2 when combined ...