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Pregnancy, Childbirth, and HIV

Children (Ages 0-17)

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3-Drug Antiretroviral Therapy Best for Preventing Vertical Transmission to Infants: Results From the PROMISE Study Img

3-Drug Antiretroviral Therapy Best for Preventing Vertical Transmission to Infants: Results From the PROMISE Study

Taking a three-drug antiretroviral therapy combination in pregnancy was more effective in preventing mother-to-child transmission than taking one drug during pregnancy, another in labor and two after delivery.

Ms. Mississippi Not Cured of HIV. What Next? A Blog Entry by Benjamin Young, M.D., Ph.D. Img

Ms. Mississippi Not Cured of HIV. What Next? A Blog Entry by Benjamin Young, M.D., Ph.D.

The not-cured Mississippi child is "another HIV-infected child whose health was failed by the weaknesses in our community and health care systems," writes experienced HIV clinician Benjamin Young, M.D., Ph.D. "Unless we actively insist on doing bette...

Early HIV Treatment in Infants: The Canadian Experience Img

Early HIV Treatment in Infants: The Canadian Experience

Initial results from the Canadian pediatric HIV research mentioned in a recent blog post were published in Clinical Infectious Diseases on June 9th. The paper notes that Canada's three pediatric HIV care institutions have a longstanding policy of adm...

Wrestling With the Implications of the Mississippi Case Img

Wrestling With the Implications of the Mississippi Case

Understandably, there has been extensive media coverage of the announcement that HIV has rebounded in the "Mississippi child." Although a full discussion of the implications will take time, there are some points that may be worth noting now, accordin...

No Longer Cured: HIV Relapse in "Mississippi Child" Raises New Questions Img

No Longer Cured: HIV Relapse in "Mississippi Child" Raises New Questions

Undoubtedly, the biggest HIV story last year was the functional cure of an infant from Mississippi after antiretroviral treatment was started within hours after her birth. Unfortunately, earlier this month during a routine check up, the child -- now ...

"Mississippi Baby" Now Has Detectable HIV, Researchers Find Img

"Mississippi Baby" Now Has Detectable HIV, Researchers Find

The child known as the "Mississippi baby" -- an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in The New England Journal of Medicine last fall -- now has detectable levels of HIV after more ...

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Very Early Treatment Benefits and Possible HIV Eradication

From the "Berlin Patient" to the "Mississippi Baby," we're gaining an appreciation for the possible benefits and utility of very early antiretroviral therapy (ART). Several studies at CROI 2014 explored this subject. In a study of HIV infection using...

Update on Mississippi Child Cured of HIV, Plus Second Child Shows Signs of HIV Remission Img

Update on Mississippi Child Cured of HIV, Plus Second Child Shows Signs of HIV Remission

One year ago this week, we first learned that a baby had been functionally cured of HIV. This week, we got an update on her health -- and word of another baby who may also be in "HIV remission."

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Mississippi Baby Cured: One Study Whose Impact Will Last Well Beyond CROI 2013

Much has already been discussed and written about the remarkable case of this infant girl born in Mississippi to an HIV-infected, but undiagnosed, woman who also didn't get any prenatal care; but if you haven't yet heard:

The mother was confirmed to...

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Report of a Functional Cure in an HIV-Infected Infant

On Monday March 4th at the Conference on Retroviruses and Opportunistic Infections (CROI) in Atlanta, details were presented on a case of a potential "functional cure" of HIV infection in an infant. The story has already broken widely in the media du...