A fascinating lecture at this year's HIVR4P conference showed how advances in modern scanning technologies can be used to get more accurate information about the first stages of HIV infection and on the ways that HIV drugs are absorbed and distribute...
Gauging treatment priority when CD4 count is high; the effect of hepatitis C coinfection on response to HIV treatment; HIV, aging and comorbidity in Africa; PrEP and drug-resistant gonorrhea.
For the first time, scientists have shown a relationship between the proportion of key immune cells that display high levels of a gut-homing protein called alpha-4 beta-7 at the time of HIV infection and health outcomes.
During the early stages of infection, HIV mounts a severe and prolonged attack on the gut, which harbors a rich population of CD4 T cells. Watch a two-minute animation describing the process.
One study in Amsterdam deployed a strategy to identify acute HIV in men who have sex with men (MSM) and then link newly diagnosed individuals to care.
Number of viral load blips during antiretroviral therapy begun during acute HIV infection predicted viral rebound when treatment stopped in a 228-person international study.
Elevated markers of inflammation and coagulation declined toward normal during treatment for acute HIV infection in a 247-person study. But other markers of disease signals remained above normal through 96 weeks of treatment.
Even in very early HIV infection -- before fourth generation HIV test assays are able to detect HIV infection -- immune activation and inflammatory processes may already be occurring.
People expected the START study results to be good. But they never expected them to be this good.
An 18-year-old female has been able to maintain an undetectable viral load for more than 12 years after interrupting early antiretroviral treatment, according to a study presented at IAS 2015.