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HIV Treatment Strategies

Managing HIV Drug Resistance

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The Curious Case of M184V, Part 1 Img
News

The Curious Case of M184V, Part 1

Paul Sax, M.D., writes that for those seeing HIV patients on a regular basis, the question "what should be done after M184V?" is both quite relevant clinically and, surprisingly, not readily answerable from the literature.

Cell Particles May Help Spread HIV Infection, NIH Study Suggests Img

Cell Particles May Help Spread HIV Infection, NIH Study Suggests

HIV appears to enlist the aid of nano-sized structures released by infected cells to infect new cells, according to a study by researchers at the National Institutes of Health.

Ibalizumab Is Effective at Reducing HIV Viral Load in People With Few Treatment Options Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Ibalizumab Is Effective at Reducing HIV Viral Load in People With Few Treatment Options

A study showed that a new monoclonal antibody drug called ibalizumab reduced viral loads in individuals with multi-drug resistant HIV. Adding the drug to a failing regimen may help treatment-experienced people who have few options to control their vi...

Pre-ART Drug Resistance in Rural South Africa but Limited Clinical Impact With Good Adherence Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Pre-ART Drug Resistance in Rural South Africa but Limited Clinical Impact With Good Adherence

The prevalence of transmitted drug resistance is above the WHO threshold of 5% in this study conducted in rural South Africa.

HIV Researchers Reassert Treatment Is Prevention Img
CROI (Conference on Retroviruses and Opportunistic Infections)

HIV Researchers Reassert Treatment Is Prevention

"We need to meet people where they are at. If you do not want to have a medical provider, but you are interested in being on [pre-exposure prophylaxis], then we should create an environment where it is possible for you to get that," says Matthew Gold...

One-Third in Care for HIV in the U.S. Had Detectable Viral Load in 2012-2013 Img

One-Third in Care for HIV in the U.S. Had Detectable Viral Load in 2012-2013

One-third -- more often women, blacks, Hispanics and younger people -- of those in HIV care had detectable viral loads that could pose a risk for HIV transmission.

No HIV Transmissions in Couples With Positive Partner Undetectable on Treatment Img
News

No HIV Transmissions in Couples With Positive Partner Undetectable on Treatment

HIV-positive individuals with a viral load below 200 while on antiretroviral therapy did not transmit HIV to steady sex partners during more than one year of condomless sex.

HIV Undetectable Does Equal Uninfectious: The Swiss Statement and the Vindication of Pietro Vernazza Img

HIV Undetectable Does Equal Uninfectious: The Swiss Statement and the Vindication of Pietro Vernazza

You cannot, the statement said, pass on HIV. The Swiss Statement was a public policy salvo lobbed into the heart of the HIV world, prompting an intense backlash. Today, it's a fact. Heather Boerner reports.

Assessing Benefits of Pre-Exposure Prophylaxis Relative to Risks of Drug Resistance Img
Conference Coverage

Assessing Benefits of Pre-Exposure Prophylaxis Relative to Risks of Drug Resistance

"Resistant infections during PrEP [pre-exposure prophylaxis] should be weighed against the numbers of infections averted," stated renowned HIV prevention and PrEP (pre-exposure prophylaxis) researcher Robert Grant, M.D., M.P.H., during a PrEP-focused...

Negligible Risk: Updated Results From Two Studies Continue to Show That Antiretroviral Treatment and an Undetectable Viral Load Is a Highly Effective HIV Prevention Strategy Img
News

Negligible Risk: Updated Results From Two Studies Continue to Show That Antiretroviral Treatment and an Undetectable Viral Load Is a Highly Effective HIV Prevention Strategy

Interim analyses from two important studies clearly demonstrated that ART and an undetectable viral load is a highly effective HIV prevention strategy for heterosexual and gay male serodiscordant couples.