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HIV Treatment Strategies

HIV Treatments in Development

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A Review of Late-Stage HIV Antiretroviral Candidates at IDWeek 2017 Img
IDWeek

A Review of Late-Stage HIV Antiretroviral Candidates at IDWeek 2017

Highlights of major findings on new antiretroviral therapies, including data on long-acting injectable solutions and new combination treatments packed into a single pill.

Effects of the Anti-Inflammatory Antibody Canakinumab on Heart Disease and Cancer: Implications for HIV? Img

Effects of the Anti-Inflammatory Antibody Canakinumab on Heart Disease and Cancer: Implications for HIV?

New study results prompt the question of whether canakinumab or other anti-inflammatories could have salutary clinical effects in HIV-positive people.

Report From the 2017 IAS HIV Cure and Cancer Forum Img
Cancer

Report From the 2017 IAS HIV Cure and Cancer Forum

Many approaches being pursued as cancer therapeutics are also being studied in the context of HIV cure research, including immune checkpoint inhibitors, cytokine therapies, genetically modified chimeric antigen receptor (CAR) T cells and other gene t...

HIV Cure Research Strategy for Women: Where Are We? Img
USCA (U.S. Conference on AIDS)

HIV Cure Research Strategy for Women: Where Are We?

Women are drastically underrepresented in HIV cure research studies. The need for a cure is critical, but will the search for HIV cure strategies include women?

MK-8591: Further Compelling Early Results for Both Treatment and Prevention Img
IAS (International AIDS Society) Conference

MK-8591: Further Compelling Early Results for Both Treatment and Prevention

Two interesting early studies on the investigational NRTI MK-8591 (EFdA) were presented at IAS 2017. This compound is notable for a very high potency, a long-half life and the potential for use both as HIV treatment and for HIV prevention.

Understanding Exactly How the 'Berlin Patient' Was Cured Img

Understanding Exactly How the 'Berlin Patient' Was Cured

A report on three other cases of HIV-infected individuals receiving stem cell transplants indicates the likely role that CCR5 mutation plays in HIV remission or cure.

HIV Pipeline Drugs: IAS 2017 Update Img
IAS (International AIDS Society) Conference

HIV Pipeline Drugs: IAS 2017 Update

A review of HIV drugs in development that summarizes the most exciting new research over the previous year.

Scientists Hone in on the Best Way to Expose HIV Hidden in the Viral Reservoir, a Crucial Step Toward an Eventual Cure Img

Scientists Hone in on the Best Way to Expose HIV Hidden in the Viral Reservoir, a Crucial Step Toward an Eventual Cure

Researchers at the University of North Carolina identified a better dosing strategy for a drug that exposes HIV hiding inside the body's viral reservoir, according to a new study.

Phase 3 Results With Bictegravir -- A New Integrase Inhibitor Combined With FTC/TAF Img
IAS (International AIDS Society) Conference

Phase 3 Results With Bictegravir -- A New Integrase Inhibitor Combined With FTC/TAF

Two studies presented at IAS 2017 showed bictegravir to be very similar in efficacy to dolutegravir with slight differences in the formulations linked to the background NRTIs in the fixed-dose combinations.

HIV Remission News From IAS 2017 Img
IAS (International AIDS Society) Conference

HIV Remission News From IAS 2017

Treatment Action Group's Richard Jefferys provides a comprehensive overview of HIV remission presentations at the 9th International AIDS Society Conference on HIV Science.