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HIV Treatment Strategies

HIV Treatments in Development

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Gene Therapy in HIV Cure Research Img
News

Gene Therapy in HIV Cure Research

There is a great deal of interest in exploring the potential of gene therapy to cure HIV and multiple gene therapy strategies are under investigation.

Why Finding New HIV Targets Takes So Long: Some Basics About Basic Research Img
News

Why Finding New HIV Targets Takes So Long: Some Basics About Basic Research

The death toll from HIV/AIDS continues to decline, but more than 36 million people are still living with HIV. A researcher explains why the work for a cure is painstaking.

An Overview of Censavudine (Festinavir) Img

An Overview of Censavudine (Festinavir)

Other Names: 4'-Ed4T, 4'-ethynyl-d4T, 4'-ethynylstavudine, BMS-986001, OBP-601, festinavir Drug Class: Nucleoside Reverse Transcriptase Inhibitors Molecular Formula: C12 H12 N2 O4 Registry Number: 634907-30-5 (CAS) Chemical Name: 1-[(2R,5R)-5-ethyny...

Enhancing Immunity: Manipulating the Immune System to Tackle HIV Img

Enhancing Immunity: Manipulating the Immune System to Tackle HIV

In the search for a cure, multiple clinical trials are investigating whether immune-based approaches can deliver the "kill" in "kick and kill."

Weight Gain When Switching From Efavirenz to an Integrase Inhibitor Img

Weight Gain When Switching From Efavirenz to an Integrase Inhibitor

Virally suppressed people who swapped an efavirenz regimen for one based on an integrase inhibitor gained significantly more weight over 18 months than those who stayed with efavirenz or switched to a protease inhibitor.

Latent Tendencies: New Strategies Target Dormant HIV Img

Latent Tendencies: New Strategies Target Dormant HIV

A major focus of HIV cure research is on reversing HIV latency -- essentially switching on the latent virus's DNA machinery so that it starts making proteins.

Measuring the HIV Reservoir: Current Tests for Sizing Up Viral Hideouts Img

Measuring the HIV Reservoir: Current Tests for Sizing Up Viral Hideouts

There are a variety of technologies available to accurately quantify the latent HIV reservoir, but each has pros and cons.

The Challenge of Defining an HIV Cure Img

The Challenge of Defining an HIV Cure

As the research effort to develop a safe, effective, broadly accessible HIV cure expands, the issue of how to measure success remains central.

Additional Remission Cases Published Img

Additional Remission Cases Published

Two recent case reports of temporary HIV remission, first presented at this year's CROI and IAS conferences, have now been published in the open access journal PLoS Medicine.

NIH Launches HIV Prevention Trial of Long-Acting Injectable Medication in Sexually Active Women Img
Women

NIH Launches HIV Prevention Trial of Long-Acting Injectable Medication in Sexually Active Women

The first large-scale clinical trial of a long-acting injectable medication for HIV prevention in sexually active women has begun and will examine whether cabotegravir injected once every eight weeks can safely protect women at risk for HIV infection...