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HIV Treatment Strategies

HIV Treatments in Development

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Combining Broadly Neutralizing Antibodies Shows Promise Img

Combining Broadly Neutralizing Antibodies Shows Promise

Results from the first human trials of a dual broadly neutralizing antibodies regimen appeared effective, safe, and well tolerated.

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News

What Is the State of the Art in HIV Treatment and Prevention?

With several new regimens nearing late-stage trials, a new generation of HIV antiretrovirals may soon be entering the marketplace.

The CHAMP Study: Clues to Natural Control of HIV Infection Img

The CHAMP Study: Clues to Natural Control of HIV Infection

Steven Deeks, M.D., and colleagues seek to define the frequency of "post-treatment controllers," who maintain control of HIV growth after discontinuing antiretroviral therapy.

Pregnant woman with pill bottle
Women

Making Clinical Trials of PrEP More Inclusive of Women, No Matter Their Pregnancy Status

Three new trials of HIV prevention drugs seek to answer directly a question that researchers inside and outside the field of HIV have explicitly avoided for years: How do drugs work -- and are they safe -- in pregnant and breastfeeding women?

NIH Launches Study to Test Combination Antibody Treatment for HIV Infection Img

NIH Launches Study to Test Combination Antibody Treatment for HIV Infection

An early phase clinical trial testing infusions of combination antibodies in people living with HIV has begun to evaluate whether periodic infusions of two highly potent, HIV-specific, broadly neutralizing antibodies are safe in people living with HI...

Post-AIDS 2018 Updates on HIV Cure Research Img

Post-AIDS 2018 Updates on HIV Cure Research

In the aftermath of the 22nd International AIDS Conference (AIDS 2018), there has been some reflecting on the challenges facing the HIV cure research field.

Studying HIV Persistence in Liver Macrophages Img

Studying HIV Persistence in Liver Macrophages

Invesitgators sought to determine whether human liver macrophages can sequester infectious HIV in people on antiretroviral therapy.

Potential New Targets to Block HIV Latency Img

Potential New Targets to Block HIV Latency

Researchers have demonstrated that HIV latency can be maintained in actively growing cells, a finding that may open new avenues to abolishing latency.

More People With HIV Virally Suppressed on Doravirine Than Darunavir at 96 Weeks, Study Shows Img

More People With HIV Virally Suppressed on Doravirine Than Darunavir at 96 Weeks, Study Shows

After 96 weeks, more people achieved viral suppression on a doravirine-based antiretroviral drug regimen compared with a darunavir (Prezista)-based one, according to data presented at the recent 22nd International AIDS Conference.

Sex and the HIV Reservoir: New Research Points to the Powerful Effect of Estrogen Img
Women

Sex and the HIV Reservoir: New Research Points to the Powerful Effect of Estrogen

A newly published study suggests that women may respond differently than men to some HIV curative interventions that are currently under investigation or, perhaps, that an effective HIV cure for women could differ from a cure for men.