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HIV Treatment Strategies

HIV Treatments in Development

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Should HIV Cure Research, Inspired by Advances in Fighting Cancer, Aim for Remission Not Eradication?

While a true cure remains elusive for both diseases, HIV researchers are looking at new advances in immuno-oncology for clues on how to achieve durable HIV remission.

Cure panel at AIDS 2016
Conference Coverage

With HIV Cure Research on the Horizon, Exploring Ethical Questions in Advance

At AIDS 2016, a multidisciplinary panel of researchers discussed the ethical questions they have already attempted to answer, quandaries their explorations have revealed and common concerns and themes that are shaping the future of HIV cure studies....

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Conference Coverage

How Can Community Engagement Support HIV Cure Research?

What is Good Participatory Practice (GPP)? Already the gold standard of HIV prevention research, these guidelines provide blueprints for engagement with a variety of stakeholders in research design and implementation. This approach can forge pathways...

What Would Motivate, or Deter, Participation in HIV Cure Research? Img
Conference Coverage

What Would Motivate, or Deter, Participation in HIV Cure Research?

Knowing that participation in HIV cure research could pose health risks to participants without providing them direct benefits, a central ethical consideration in this area is what motivates participants to get involved.

Jennifer Power, Ph.D., of La...

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Conference Coverage

How Do We Define 'HIV Cure'?

What is a "cure," anyway? Not one presentation during this session failed to note the complicated semantic knots wrapped around the term "HIV cure" and the implications of misconceptions in securing authentic informed consent and community comprehens...

Researchers, Policy Makers, Volunteers See Different Risks of HIV Cure Research Img
Conference Coverage

Researchers, Policy Makers, Volunteers See Different Risks of HIV Cure Research

In an online survey and personal interviews, researchers, policy makers and potential trial volunteers with HIV infection underlined different perceived risks in HIV cure research.

Personal Clinical Benefits in HIV Cure Trials: Unlikely But Motivating Img
Conference Coverage

Personal Clinical Benefits in HIV Cure Trials: Unlikely But Motivating

Regulators and HIV cure researchers in the United States concur that early cure studies have little chance of conferring direct clinical benefits on volunteers, according to the results of in-depth interviews.

Dr. Lewin speaks at the Towards an HIV Cure Symposium, Durban, South Africa, July 2016 (Credit: International AIDS Society/Steve Forrest/Workers' Photos)
Conference Coverage

Can Cancer Treatments Pave the Way to a Cure for HIV?

"There are many overlaps in HIV cure research and cancer research," Sharon Lewin, M.D., says. "In cancer you're going after these few cells that are left so the cancer won't come back and in HIV you're trying to reach the few persistent cells that ar...

The Current State of HIV Cure Research: An Interview With Carl Dieffenbach Img

The Current State of HIV Cure Research: An Interview With Carl Dieffenbach

In this interview, Carl Dieffenbach, Ph.D., director of the Division of AIDS, National Institute of Allergy and Infection Diseases (NIAID), shares his thoughts on the challenges and opportunities ahead on the road toward an HIV cure.

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The Ethics of HIV Cure Trials

When it comes to clinical trials for HIV cures, many patient volunteers may be asked to stop taking their once-daily medicines to measure the true effect of the experimental treatment, raising ethical questions and concerns.