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HIV Treatments in Development

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Advances in HIV Latency Leading to New Cure Approaches Img

Advances in HIV Latency Leading to New Cure Approaches

Using a test tube model, researchers have been able to link specific non-coding RNAs to a group of proteins involved in establishing HIV latency.

GSK Discontinues Development of Maturation Inhibitor BMS-955176 Img

GSK Discontinues Development of Maturation Inhibitor BMS-955176

GlaxoSmithKline announced that is has stopped development of its lead maturation inhibitor. Already in phase 2b studies, it was hoped BMS-955176 would provide a new option for people with multi-drug resistant HIV.

Jacob Lalezari, M.D., and Daniel Kuritzkes, M.D.
IDWeek

Extensively Drug-Resistant HIV Yields to a New Drug: Ibalizumab

HIV clinicians who have patients in declining health due to extensive HIV drug resistance may soon have a new lifesaving option. Ibalizumab, an HIV entry inhibitor in development, shows highly encouraging antiretroviral activity in the days after it ...

What's Hot in HIV Cure Research? Img
IDWeek

What's Hot in HIV Cure Research?

When it comes to an HIV cure, what do we know now and what are the main areas of focus for future research? Irini Sereti, M.D., reviewed and analyzed the current strategies in cure research, during a presentation at IDWeek 2016 in New Orleans.

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IDWeek

What's Hot in HIV Cure Research?

When it comes to an HIV cure, what do we know now and what are the main areas of focus for future research? Irini Sereti, M.D., reviewed and analyzed the current strategies in cure research, during a presentation at IDWeek 2016 in New Orleans.

Antibody Therapy Leads to Sustained Post-Treatment SIV Control in Macaques Img

Antibody Therapy Leads to Sustained Post-Treatment SIV Control in Macaques

"The results of the study appear very encouraging, and the researchers are hoping to rapidly evaluate whether they have any relevance to humans," Richard Jefferys writes. "A small clinical trial of the anti-α4β7 antibody vedolizumab, which is FDA-app...

Scientists at NIH and Emory Achieve Sustained SIV Remission in Monkeys Img

Scientists at NIH and Emory Achieve Sustained SIV Remission in Monkeys

Scientists at the National Institutes of Health (NIH) and Emory University have experimentally induced sustained remission of SIV, the simian form of HIV, in infected monkeys.

The Reprieve Study Comes to Canada Img
Cardiovascular

The Reprieve Study Comes to Canada

Researchers in the U.S., Canada and Thailand are conducting a large HIV and cardiovascular disease study on a relatively new statin called pitavastatin.

The Trauma of Hope: A Psychotherapist Reflects on False Cure News -- A Blog Entry by Keiko Lane Img

The Trauma of Hope: A Psychotherapist Reflects on False Cure News -- A Blog Entry by Keiko Lane

"Hope triggers a particular kind of trauma made complicated by its relationship to grieving," writes Keiko Lane, MFT. "The relentless activation is exhausting and antithetical to the emotional stability required for long-term resilience."

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Should HIV Cure Research, Inspired by Advances in Fighting Cancer, Aim for Remission Not Eradication?

While a true cure remains elusive for both diseases, HIV researchers are looking at new advances in immuno-oncology for clues on how to achieve durable HIV remission.