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HIV Treatment Strategies

HIV Treatments in Development

The Latest

Bictegravir versus Dolutegravir: Phase 2 Results of New Integrase Inhibitor Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Bictegravir versus Dolutegravir: Phase 2 Results of New Integrase Inhibitor

Early results presented at CROI 2017 show the potential for bictegravir to be an important antiretroviral.

New NNRTI Doravirine Is Non-Inferior to Darunavir/Ritonavir in Phase 3 Treatment-Naive Study Img
CROI (Conference on Retroviruses and Opportunistic Infections)

New NNRTI Doravirine Is Non-Inferior to Darunavir/Ritonavir in Phase 3 Treatment-Naive Study

48-week results from a phase 3 study comparing the NNRTI doravirine to boosted darunavir showed similar viral suppression and low rates of side effects.

Pharmacokinetics and Full Phase 2 Results for Bictegravir, a New Integrase Inhibitor Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Pharmacokinetics and Full Phase 2 Results for Bictegravir, a New Integrase Inhibitor

Two oral presentations on a new integrase inhibitor bictegravir were included in the first session at CROI 2017 looking at new treatment and treatment strategies.

Antibodies Could Offer a More 'Natural' and Safer HIV Treatment or Prevention Option Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Antibodies Could Offer a More 'Natural' and Safer HIV Treatment or Prevention Option

At CROI 2017, Richard Kroup, M.D., from NIAID provided an overview of the recent advances in antibody treatments for HIV prevention and treatment.

CROI 2017 Preview: New Research on HIV Cure and Treatment Img
CROI (Conference on Retroviruses and Opportunistic Infections)

CROI 2017 Preview: New Research on HIV Cure and Treatment

Here's a preview of some of the noteworthy HIV cure and treatment research being presented at CROI 2017 in Seattle.

Exciting Results in Monkeys Lead to a Clinical Trial in Humans Img

Exciting Results in Monkeys Lead to a Clinical Trial in Humans

An HIV cure research experiment that treated monkeys with a4b7 antibodies yielded unexpected and promising results.

The Search for a Cure Img

The Search for a Cure

In the quest for a cure for HIV, many different approaches are being tested, with many clinical trials underway in the U.S.

Safety Issues With Vedolizumab Img

Safety Issues With Vedolizumab

In the search for a cure, the antibody vedolizumab (Entyvio) will likely draw much interest for testing with HIV-positive people.

Targeting Latently Infected Cells via IFITM1 Img

Targeting Latently Infected Cells via IFITM1

HIV cure researchers seek out markers that would allow the specific targeting of cells harboring latent HIV. Enter a new candidate: interferon-induced transmembrane protein 1 (IFITM1).

Gene Therapy to Cure HIV: Where to From Here? Img

Gene Therapy to Cure HIV: Where to From Here?

"Despite the challenges, gene therapy is a promising avenue in the quest for a cure," amfAR's Rowena Johnston, Ph.D., says.