https://www.thebodypro.com/category/hiv-treatments-in-development
HIV Treatment Strategies

HIV Treatments in Development

The Latest

New Drugs, New Hope and Possible Timelines Img
CROI (Conference on Retroviruses and Opportunistic Infections)

New Drugs, New Hope and Possible Timelines

At the recent Conference on Retroviruses and Opportunistic Infections, researchers presented data about 5 new anti-HIV compounds in development.

Do Integrase Inhibitors Affect Testosterone Levels in Men? Img
Endocrine/Sexual Dysfunction

Do Integrase Inhibitors Affect Testosterone Levels in Men?

In a small cross-sectional study researchers found a link between the use of integrase inhibitors and the presence of low testosterone, but they may have inadvertently arrived at this conclusion.

Increased Risk of IRIS With Integrase Inhibitors Reported in Two Studies Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Increased Risk of IRIS With Integrase Inhibitors Reported in Two Studies

Two cohort studies presented at CROI 2017 showed a higher risk of IRIS with integrase inhibitor-based ART than with other regimens.

Flagging the HIV Reservoir: A Potential New Marker for CD4 Cells Hiding HIV Img

Flagging the HIV Reservoir: A Potential New Marker for CD4 Cells Hiding HIV

New research shows that it may be possible to identify many latently infected CD4 T cells due to expression of a particular cell surface protein.

Long-Acting Cabotegravir Injection Protects Macaques From SIV Img

Long-Acting Cabotegravir Injection Protects Macaques From SIV

One injection of long-acting cabotegravir (CAB LA) protected 21 of 24 macaques from intravenous challenge with simian immunodeficiency virus (SIV).

Monkeys Suppress HIV-Like Virus for Extended Period After Dual-Antibody Treatment Img

Monkeys Suppress HIV-Like Virus for Extended Period After Dual-Antibody Treatment

Giving monkeys two powerful anti-HIV antibodies immediately after infection with an HIV-like virus enabled the immune systems of some of the animals to control the virus long after the antibodies were gone.

3 Broadly Neutralizing Antibodies May Explain How Individual Controls HIV Without Treatment Img

3 Broadly Neutralizing Antibodies May Explain How Individual Controls HIV Without Treatment

Three broadly neutralizing antibodies in an HIV-positive person may explain how this individual controlled HIV for 30 years without antiretroviral therapy.

New HIV Capsid Inhibitor Strongly Stops HIV Replication at Two Steps Img
CROI (Conference on Retroviruses and Opportunistic Infections)

New HIV Capsid Inhibitor Strongly Stops HIV Replication at Two Steps

A first-in-class HIV-1 capsid inhibitor interrupts replication at two steps of the viral lifecycle and has pharmacokinetic properties that may permit once-monthly or less frequent dosing.

Antibody Therapies Effective at Preventing HIV From Invading CD4 Cells Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Antibody Therapies Effective at Preventing HIV From Invading CD4 Cells

Two new monoclonal antibodies demonstrated success in helping people living with HIV suppress their viral loads to undetectable levels.

Pregnancy Common in ART Trials in Sub-Saharan Africa Despite Exclusion Criteria Img

Pregnancy Common in ART Trials in Sub-Saharan Africa Despite Exclusion Criteria

A new analysis reports that HIV-positive women in clinical trials in sub-Saharan Africa are likely to get pregnant as often as those receiving care outside of research settings.