HIV Treatments in Development

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This Week in HIV Research: One Step at a Time

June 13, 2019: Integrated stepped alcohol treatment in HIV clinics; cytokines, inflammation, and heart risk; impact of CCR5 gene editing on lifespan; the costs of "test and treat" for hepatitis C.

By Barbara Jungwirth and Myles Helfand

This Week in HIV Research: Matters of the Heart

May 30, 2019: Myocardial infarction risk among people with HIV; dolutegravir vs. efavirenz; a new way to estimate date of seroconversion; identifying people at imminent risk for disengagement from care.

By Barbara Jungwirth and Myles Helfand

Long-Acting HIV Treatment Is Coming. Our Health Care System Needs to Prepare

Providers, payers, and health systems need to catch up, said Melanie Thompson, M.D., at the ACTHIV conference.

By Kenyon Farrow

The Genetic Mutation Behind the Only Apparent Cure for HIV

The HIV-resistant gene mutation CCR5 delta 32 has an interesting past. Could it also be the future of HIV treatment and prevention?

By Martha Kempner

Phase 3 Results With Dual Therapy Cabotegravir/Rilpivirine Long-Acting Injections: ATLAS and FLAIR Studies

Two oral presentations at CROI 2019 showed that dual therapy with long-acting monthly injections resulted in very low levels of virological failure with high participant preference for injections compared to oral combinations.

By Simon Collins for HIV i-Base

What You Need to Know About the Second Person Likely Cured of HIV

Richard Jefferys, an expert in HIV cure research, spoke to TheBodyPro about this new case of HIV remission -- and the danger in rushing to publish these stories, especially for people who live with stigma.

By Kenyon Farrow

The Only Cases of HIV Cure or Remission

Over the past few years, a tiny – but slowly growing – number of people appeared to have had active, living, reproducing HIV completely eliminated from their bodies.

By Warren Tong and Myles Helfand

UK Patient Likely to Be the Second Person Cured of HIV: Two Further Cases at CROI 2019 of HIV Remission After Allogenic Stem Cell Transplants

The procedure used in this case was similar to that used in the only previously confirmed HIV cure case, "Berlin patient" Timothy Ray Brown, albeit with a somewhat less aggressive approach.

By Simon Collins for HIV i-Base

Are Integrase Inhibitors Linked to Weight Gain? An Evidence Review

Integrase inhibitors are associated with greater increases in body weight than other antiretrovirals, especially among women and black people. But it's unclear whether these changes are clinically significant.

By Polly Clayden for HIV i-Base