HIV Treatments in Development

The Latest

Long-Acting HIV Treatment Is Coming. Our Health Care System Needs to Prepare

Providers, payers, and health systems need to catch up, said Melanie Thompson, M.D., at the ACTHIV conference.

By Kenyon Farrow

The Genetic Mutation Behind the Only Apparent Cure for HIV

The HIV-resistant gene mutation CCR5 delta 32 has an interesting past. Could it also be the future of HIV treatment and prevention?

By Martha Kempner

Phase 3 Results With Dual Therapy Cabotegravir/Rilpivirine Long-Acting Injections: ATLAS and FLAIR Studies

Two oral presentations at CROI 2019 showed that dual therapy with long-acting monthly injections resulted in very low levels of virological failure with high participant preference for injections compared to oral combinations.

By Simon Collins for HIV i-Base

What You Need to Know About the Second Person Likely Cured of HIV

Richard Jefferys, an expert in HIV cure research, spoke to TheBodyPro about this new case of HIV remission -- and the danger in rushing to publish these stories, especially for people who live with stigma.

By Kenyon Farrow

The Only Cases of HIV Cure or Remission

Over the past few years, a tiny – but slowly growing – number of people appeared to have had active, living, reproducing HIV completely eliminated from their bodies.

By Warren Tong and Myles Helfand

UK Patient Likely to Be the Second Person Cured of HIV: Two Further Cases at CROI 2019 of HIV Remission After Allogenic Stem Cell Transplants

The procedure used in this case was similar to that used in the only previously confirmed HIV cure case, "Berlin patient" Timothy Ray Brown, albeit with a somewhat less aggressive approach.

By Simon Collins for HIV i-Base

Are Integrase Inhibitors Linked to Weight Gain? An Evidence Review

Integrase inhibitors are associated with greater increases in body weight than other antiretrovirals, especially among women and black people. But it's unclear whether these changes are clinically significant.

By Polly Clayden for HIV i-Base

The Long-Acting Bandwagon: A Top HIV Clinical Development of 2018

Word is getting out that, barring some major setback, long-acting injectable HIV antiretrovirals will soon be coming our way. Patients have come to my clinic asking about it; others muse that they wish there were shots instead of pills, and are heart...

By David Alain Wohl, M.D.

Designing HIV-Resistant People: A Top HIV Clinical Development of 2018

As unsavory as probably it is to most of us, there's big news in the claim by He Jiankui, Ph.D., that he was able to use Crispr-Cas9 technology to alter the genes of twin girls so they were born with their CD4 cells not expressing the CCR5 co-recepto...

By David Alain Wohl, M.D.

Monkey Study Uncovers the Potential for Vesatolimod and Antibodies in HIV Cure Research

Researchers hope that by interacting with the toll-like receptor protein TLR-7 an experimental drug can help increase the immune system's ability to sense and attack HIV and HIV-infected cells.

By Sean R. Hosein for Canadian AIDS Treatment Information Exchange