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Top 10 HIV Clinical Developments of 2019

Will a given development in HIV make a difference in the clinic? Will it change practice? Is this something I should know if I take care of people living with HIV? The answer to each of these must be yes for the story to make the list.

Two-Drug TANGO photo illo

TANGO, the Most Relevant Two-Drug Antiretroviral Therapy Trial of the Year

Whether lamivudine/dolutegravir is sufficient to achieve and maintain viral suppression was last year's question. As we move to 2020, a new question could be asked: Are three-drug regimens still necessary?

Long-Acting Antiretrovirals photo illo

ATLAS, FLAIR, and the Upcoming Arrival of Long-Acting Injectable HIV Treatment

The likely launch of injectable cabotegravir/rilpivirine in early 2020 will be interesting, writes David Wohl, M.D. One big question: How smoothly will the rollout go?

The DAWNING Study photo illo

DAWNING Study Casts New Light on the Details of Resistance

The findings will help providers manage patients who have known or potential resistance to NRTIs, but who we want to place on a simplified antiretroviral regimen.