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HIV Basic Science and Pathogenesis

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Scientists Discover Key Genetic Factor in Determining HIV/AIDS Risk

People with more copies of a gene that helps to fight HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a...

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Mortality Trends: Toward a New Definition of AIDS?

Changing Patterns of Mortality AIDS Then and Now Who Gets AIDS Today? How Late Is Too Late? AIDS vs. Non-AIDS Mortality Shifting Causes of Illness and Death Liver Problems Malignancies HPV-Associated Cancers HAART Risks vs. Benefi...

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HIV Replication Capacity and Treatment Decisions

Researchers have known since the mid-1990s that some versions (strains) of HIV are less potent than others. Yet only recently have a number of studies sought to determine whether reductions or increases in HIV's ability to reproduce (i.e., replicatio...

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Fauci to Present Research Update at World AIDS Conference in Bangkok

At the XVth International AIDS Conference in Bangkok, Thailand, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID) and chief of the NIAID Laboratory of Immunoregulation (LIR), will present his labora...

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Risk Factors Associated With Delayed Entry to Care

It is estimated that up to two thirds of people living with HIV in the United States are unaware of their diagnosis, or are aware of their status but are not receiving care. These individuals with delayed entry into care are at risk of developing HIV...

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Conference Coverage

Keystone HIV Pathogenesis and Vaccine Development Report

This year's Keystone Symposia on Molecular Mechanisms of HIV Pathogenesis (X7) and HIV Vaccine Development (X8) were held in British Columbia's Whistler Resort, Canada, from 12-18 April 2004.

This highly specialised and relatively small annual meeti...

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Features

HIV and Host Genetics: Complexity and Contradiction

I vividly remember the moment I understood how complex the life cycle of HIV must be and how difficult it could become to find a cure. During a press briefing at the 1989 International Conference on AIDS in Montreal, Professor Jay Levy, of the Univer...

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One-Quarter of Canadians Believe HIV Can Be Transmitted Through Kissing, Mosquito Bites, Poll Says

Approximately one in four Canadians believes HIV/AIDS can be transmitted through kissing and mosquito bites, indicating a "knowledge gap" in the general public regarding the disease, according to a recently released national poll commissioned by Heal...

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Dominant Immune System Alleles Tied to HIV Progression

In the first application of a novel statistical technique to the study of disease, researchers found that the genes underlying HIV infected patients' immune systems can predict their risk of progressing to AIDS. Analysis showed that the virus is less...

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New Theory on Origin of AIDS Virus

The same researchers who argued that humans probably first got HIV from butchering chimpanzees for food have traced the origin of the virus back one step further: to the monkeys that the chimpanzees ate. They believe the simian precursor to HIV was c...