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HIV Basic Science and Pathogenesis

Immune Reconstitution Syndrome (IRS/IRIS)

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PET scans show areas of high FDG (glucose) uptake in an individual before (pink outline) and after (blue outline) receiving antiretroviral therapy for HIV infection. In the second image, the spike in sugar-hungry cells corresponds to a diagnosis of immune

Video SNiP: PET Scan 'Hot Spots' Help Visualize Inflammatory Complication of HIV

Researchers are working to visualize and predict immune reconstitution syndrome (IRIS) in people with HIV in a new way -- with positron emission tomography (PET).

Five-Drug Early HIV Treatment Does Not Correct Inflammation or Immune Deficits Img

Five-Drug Early HIV Treatment Does Not Correct Inflammation or Immune Deficits

Starting five-drug antiretroviral therapy (ART) very early did not quell HIV-associated inflammation in a randomized comparison with standard ART.