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First-Line HIV Treatment

Conference Coverage

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TAF as Effective as TDF in Cisgender Women, With Fewer Side Effects Img

TAF as Effective as TDF in Cisgender Women, With Fewer Side Effects

A pooled analysis presented at CROI 2019 showed fewer kidney and bone density issues with tenofovir alafenamide in cisgender women than were found with the older formulation.

Phase 3 Results With Dual Therapy Cabotegravir/Rilpivirine Long-Acting Injections: ATLAS and FLAIR Studies Img

Phase 3 Results With Dual Therapy Cabotegravir/Rilpivirine Long-Acting Injections: ATLAS and FLAIR Studies

Two oral presentations at CROI 2019 showed that dual therapy with long-acting monthly injections resulted in very low levels of virological failure with high participant preference for injections compared to oral combinations.

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What's Hot in HIV Cure Research?

When it comes to an HIV cure, what do we know now and what are the main areas of focus for future research? Irini Sereti, M.D., reviewed and analyzed the current strategies in cure research, during a presentation at IDWeek 2016 in New Orleans.

Test and Treat Did Not Impact Transmission Rates in South African Study Img

Test and Treat Did Not Impact Transmission Rates in South African Study

On behalf of IFARA, Fred Schaich spoke with François Dabis, M.D., Ph.D., about a study presented at this year's International AIDS Conference on the impact of the "test and treat" strategy on HIV transmission rates.

Excellent Uptake of Test and Treat in Swaziland Pilot Project Img

Excellent Uptake of Test and Treat in Swaziland Pilot Project

The results of a "test and treat" pilot project in Swaziland presented at this year's International AIDS Conference were very positive, with a very high uptake of testing and starting treatment, good retention in care and good viral suppression.

Early HIV Treatment Lowers Transmission Risk by Up to 93%: HPTN 052 Final Results Img

Early HIV Treatment Lowers Transmission Risk by Up to 93%: HPTN 052 Final Results

Final results of HPTN 052, the watershed randomized trial that positioned antiretroviral therapy (ART) as an HIV prevention strategy, indicate that participants starting ART at a high CD4 count sustained a 93% lower risk of transmitting HIV to sex pa...

Earlier Start of Antiretroviral Therapy Impacts Aging With HIV (Video) Img

Earlier Start of Antiretroviral Therapy Impacts Aging With HIV (Video)

On behalf of IFARA, executive producer Fred Schaich spoke with Seema Desai, Ph.D., Peter Hunt, M.D., and Alan Landay, Ph.D., about managing HIV in those over 50 years old.

No Difference in Neuropsychological Test Results Between Early and Delayed Treatment in START Substudy Img

No Difference in Neuropsychological Test Results Between Early and Delayed Treatment in START Substudy

Neuropsychological test results were similar for those who started antiretroviral therapy immediately and those who waited before starting, according to a substudy in the START study.

Immediate Antiretroviral Therapy in START Study Linked to Greater Bone Loss Over Three Years Img

Immediate Antiretroviral Therapy in START Study Linked to Greater Bone Loss Over Three Years

People randomized to begin antiretroviral therapy (ART) immediately in the international START trial had steeper declines in bone mineral density (BMD) than people randomised to delayed therapy.

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HIV Antiretroviral Therapy: Past, Present and Future

In the last two decades, antiretroviral therapy has dramatically improved the health of people living with HIV. Let’s take a brief look at the past and present before we look forward to HIV treatment in 2020.