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FDA-Approved HIV Medications

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What You Don't Know, You Can Sell Img
Hepatitis C

What You Don't Know, You Can Sell

Many people with HIV also have hepatitis C. So why did it take so long to see information about potentially serious interactions between HIV drugs and Victrelis (boceprevir), a new hep C medication? Activist Tracy Swan offers this sharp critique.

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Hepatitis C

Merck Says Hepatitis Pill Hampers HIV Drugs

Merck & Co.'s hepatitis C virus (HCV) treatment Victrelis (boceprevir) considerably lessens the effectiveness of some widely used HIV drugs, U.S. regulators and Merck recently announced.

"These drug interactions may be clinically significant for pat...

Boceprevir/PI Interaction: A "Dear Doctor" Letter We Didn't Want to Get Img
Hepatitis C

Boceprevir/PI Interaction: A "Dear Doctor" Letter We Didn't Want to Get

By now I'm sure that most of you ID folks out there have received the following letter from Merck, the makers of boceprevir:

URGENT — IMPORTANT DRUG WARNING: VICTRELIS (BOCEPREVIR)

The purpose of this communication is to inform you of recent p...

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Bristol-Myers, Gilead Work on New Combo HIV Pill

Bristol-Myers Squibb Co. and Gilead Sciences Inc. announced Wednesday a deal to develop and sell a once-a-day HIV pill that combines a popular protease inhibitor (PI) with a boosting agent.

Under the plan, Bristol-Myers will formulate, manufacture, ...

ICAAC HIV Poster Roundup #1: Clinically Relevant Findings Img
News

ICAAC HIV Poster Roundup #1: Clinically Relevant Findings

Here's a quick sampling of some of the more noteworthy HIV-related posters presented at a major research conference last week. Topics covered include a surprisingly high frequency of people quitting Atripla due to side effects; the decline of multidr...

Study: HIV Risks Rise With Some Birth Control Img

Study: HIV Risks Rise With Some Birth Control

Hormone-based contraception may be associated with an increased risk both of HIV acquisition (by HIV-negative women) and HIV transmission (from HIV-positive women to men) during sex, according to a recent study. However, the findings still need to be...

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Older Adults (Ages 50+)

AIDS Drugs Can Cause Premature Aging: Study

A class of AIDS drugs has been linked with mitochondrial DNA mutations, which could help explain the premature aging and age-related illnesses seen in some HIV patients, British researchers say in a new study. The implicated class, nucleoside analog ...

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News

Tibotec and Gilead Team Up to Develop Prezista/Cobicistat Combo

Tibotec Pharmaceuticals announced on June 28 that it has entered into a license agreement with Gilead Sciences, Inc. for the development and commercialization of a new once-daily, single-tablet, fixed dose antiretroviral combination product containin...

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Quad Reduces Levels of Oral Contraceptives

This open-label fixed-sequence study investigated the pharmacokinetics of a combined oral contraceptive containing 25 µg ethinylestradiol and norgestimate with a fixed dose combination tablet containing elvitegravir, cobicistat, FTC and TDF ("Quad")....

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Elvitegravir/Cobicistat and Acid Reducing Agents

The effects of omeprazole (20 mg once daily) or famotidine (40 mg once daily) on the pharmacokinetics of EVG and cobicistat were studied in HIV-negative subjects (n=11 per group).

When omeprazole was administered 2 hours prior to elvitegravir and co...