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FDA-Approved HIV Medications

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Statin Use in HIV-Positive People

At CROI 2013, statins use in HIV management was the focus of a poster discussion and two late breaker oral presentations.

Most usefully, this poster session included an overview by Steven Grinspoon from Massachusetts General Hospital prior to the ma...

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Nevirapine-Containing ART Does Not Reduce Combined Oral Contraceptive Effectiveness

Nevirapine is associated with a 30% decrease in contraceptive hormone levels in pharmacokinetic (PK) studies. Adequately powered studies have not previously been conducted to assess clinical outcomes, such as ovulation, in women receiving concomitant...

Trip Gulick's Parody of "Do-Re-Mi" Featuring the HIV Antiretroviral Pantheon (Lyrics) Img
Conference Coverage

Trip Gulick's Parody of "Do-Re-Mi" Featuring the HIV Antiretroviral Pantheon (Lyrics)

Roy M. "Trip" Gulick, M.D., a professor of medicine and the chief of the Division of Infectious Diseases at Weill Medical College of Cornell University, took the stage at the opening session of the inaugural IDWeek conference to accept the HIV Medici...

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HIV and Its Treatment

Table of Contents

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FDA-Approved Anti-HIV Medications

Antiretroviral therapy (ART) is the recommended treatment for HIV infection. ART involves taking a combination of anti-HIV medications (a regimen) daily. A regimen contains three or more anti-HIV medications from at least two different drug classes. ...

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Hepatitis C

Considering HIV and HCV Drug Interactions

Boceprevir and telaprevir interact with some drugs used for HIV treatment (and vice versa). Most drug-drug interaction studies have been conducted using healthy HCV- and HIV-negative volunteers. Based on results from these studies, pharmacologists an...

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HIV and Telaprevir Drug Interactions

Phase III clinical trials tend to enroll carefully selected patients who have few or mild-to-moderate pre-existing health conditions. In practice, once a drug is licensed, a wide variety of patients, some of whom may have multiple health conditions, ...

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Hepatitis C

HIV and Boceprevir Drug Interactions

Phase III clinical trials tend to enroll carefully selected patients who have few or mild-to-moderate pre-existing health conditions. In practice, once a drug is licensed, a wide variety of patients, some of whom may have multiple health conditions, ...

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Intranasal and Topical Corticosteroids and Risk of Cushing's Symptoms in HIV Patients on Ritonavir-Based Combinations

Although iatrogenic Cushing's syndrome has previously been reported as a complication from the drug-drug interaction between ritonavir and corticosteroids (we included two cases in HTB last year), two posters at BHIVA this year highlighted low awaren...

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African-Americans

Warfarin and ARVs: Impact of African-American Race and Ritonavir

The commonly prescribed anticoagulant warfarin is highly susceptible to interactions with antiretroviral mediated through CYP 2C9, 2C19, and/or 3A4 pathways, although data are limited.

This retrospective, case‐control (1:2) study compared the warfar...