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FDA-Approved HIV Medications

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marijuana buds spilling out of a prescription bottle

Why HIV Care Providers Should Discuss Marijuana Use With Their Patients

What are the benefits and risks of marijuana use for people living with HIV? The answer is complicated, and explains why clinician-patient communication on the issue is increasingly important.

Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (Delstrigo)
News

Fixed-Dose Doravirine Combination Non-Inferior in Treatment-Experienced Patients

Delstrigo, a fixed-dose combination regimen containing the newly approved antiretroviral doravirine (Pifeltro), lamivudine (3TC, Epivir), and tenofovir disoproxil fumarate (Viread), was non-inferior to other triple combination therapies in participan...

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This Week in HIV Research: Where Are the Cervical Cancer Screens?

Poor rates of cervical cancer screening for women of color; interest vs. action among potential organ donors; an online depression intervention; Truvada levels in men’s vs. women’s hair.

Efavirenz Side Effects and Other Drug-Drug Interactions Are Common in Ugandan Cohort Img
Uganda

Efavirenz Side Effects and Other Drug-Drug Interactions Are Common in Ugandan Cohort

Drug-drug interactions and side effects, associated with currently-used first-line antiretroviral therapy, are under-reported and managed in Uganda.

China Approves Albuvirtide: A Once-Weekly Injectable Entry Inhibitor Img
China

China Approves Albuvirtide: A Once-Weekly Injectable Entry Inhibitor

On June 6, 2018, without news from the U.S. FDA, a press release from Frontier Biotech announced the approval of a new HIV drug in China that is given by once-weekly injection.

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This Week in HIV Research: Monday, Wednesday, Treatment Days

Happy days for thrice-weekly dosing; shortfalls in chronic opioid therapy monitoring; neurocognition, treatment initiation, and high CD4; the link between influenza virus shedding and CD4 count.

The Evolution of Antiretroviral Therapy: Past, Present, and Future Img

The Evolution of Antiretroviral Therapy: Past, Present, and Future

The detection, diagnosis, and treatment of HIV has evolved rapidly. This review summarizes the past, present, and future of antiretrovirals for the treatment and prevention of HIV.

Efavirenz Might Decrease Effectiveness of the Vaginal Contraceptive Ring Img
CROI (Conference on Retroviruses and Opportunistic Infections)

Efavirenz Might Decrease Effectiveness of the Vaginal Contraceptive Ring

Efavirenz (Sustiva, Stocrin) alters hormone exposure from the vaginal ring in HIV positive women, similar or greater to that previously reported with oral hormonal contraceptives.

Significant Drug-Drug Interaction Between Dolutegravir and Isoniazid-Rifapentine Img
Tuberculosis

Significant Drug-Drug Interaction Between Dolutegravir and Isoniazid-Rifapentine

Dolutegravir (Tivicay) given with once-weekly isoniazid-rifapentine led to marked cytokine release and serious adverse events in a drug-drug interaction study.

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Neurocognitive

This Week in HIV Research: This Is Your Brain on (HIV) Drugs

NeuroAIDS while on efavirenz vs. common NRTIs; HIV and the smoking cessation aid varenicline; PrEP adherence after positive partners start treatment; and Ugandans underreporting their antiretroviral use.