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FDA-Approved HIV Medications

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Drug Interactions and Anti-HIV Therapy

Introduction A Ubiquitous and Growing Problem Mechanisms of Drug Interactions Pharmacodynamic Effects An Introduction to Pharmacokinetics Factors That Impact Drug Interactions Interactions Involving Antiretrovirals Interactions With O...

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Notice of Important New Drug Interactions With Norvir, Kaletra

The Norvir (ritonavir) and Kaletra (lopinavir/ritonavir) package inserts (product labeling) were recently updated to include information regarding interactions with fluticasone (a synthetic corticosteroid, the active component of Flonase nasal Spray)...

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Safety and Pharmacokinetic Data for 640385, a New Protease Inhibitor in Development

In July 2003, during the 2nd International AIDS Society Conference on Pathogenesis and Treatment, which was held in Paris, France,1 data were presented about the in vitro anti-HIV activity of a new protease inhibitor (PI) called 640385 (also known as...

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Tuberculosis

Drug Interaction Warning: Saquinavir/Ritonavir and Rifampin (Rifampicin, Rifadin, Rimactane, Rofact)

Roche Laboratories Inc. has issued a "Dear Health Care Provider" letter (PDF) to communicate an important drug interaction warning for saquinavir/ritonavir, used as part of combination therapy for treatment of HIV infection:

Drug-induced hepatitis w...

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Psychiatric and HIV Medication Interactions

CategoryNNRTIsNRTIsPIsSSRIsProzac increases levels of Rescriptor 50%NPDProzac may lead to increased effects of Norvir, but no dose adjustment of Norvir is needed when used in combination. Norvir increases levels of Prozac, Luvox, Paxil, and Zoloft.TC...

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Anti-HIV Drug Identification Chart: United States

Generic NameBrand NameAbbreviationPharmaceutical Co.Nucleoside Analog Reverse Transcriptase Inhibitors (NRTIs) & Nucleotide Analog Reverse Transcriptase Inhibitors (NtRTIs)abacavirZiagenABVGlaxoSmithKlinedidanosineVidexddIBristol-Myers Squibbdida...

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Atazanavir, With or Without Ritonavir, Should Not Be Coadministered With Proton Pump Inhibitors

Bristol-Myers Squibb has issued a Dear Healthcare Provider letter regarding important new pharmacokinetic data concerning the coadministration of Reyataz (atazanavir) and Norvir (ritonavir) with Prilosec (omeprazole). Omeprazole is a proton-pump inhi...

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How HIV Drugs Work

There are currently five categories of HIV antiviral drugs available that have FDA (U.S. Food and Drug Administration) approval. These categories are:

nucleoside reverse transcriptase inhibitors (NRTIs)

nucleotide reverse transcriptase inhibitors (...

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Cardiovascular

Warning Against Using Erythromycin (Even Orally) While Using Protease Inhibitors or Certain Other Drugs

An article in the September 9, 2004 New England Journal of Medicine reported that patients using the antibiotic erythromycin at the same time as drugs that strongly inhibited cytochrome P-450 3A (CYP3A, an enzyme in the liver that helps remove many d...

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Drug Interactions Fact Sheet

Introduction Drug List Glossary of Terms Anti-HIV Medications + Street Drugs: Some Cocktails Don't Mix

Introduction

With the number of drugs available to treat HIV and with those that prevent or treat opportunistic infections (OIs), the pot...