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Etravirine (Intelence)

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Pharmacokinetics in Pregnancy: Darunavir/Ritonavir and Etravirine Img
News

Pharmacokinetics in Pregnancy: Darunavir/Ritonavir and Etravirine

Two small studies presented at the 5th International Workshop on HIV & Women evaluated the pharmacokinetics of darunavir/ritonavir (DRV/r) and etravirine (ETV) respectively in pregnancy. In both studies drug exposure was altered -- lower for DRV and ...

Pharmacokinetics of Antiretrovirals in Pregnancy: Rilpivirine, Etravirine and Raltegravir Img
Conference Coverage

Pharmacokinetics of Antiretrovirals in Pregnancy: Rilpivirine, Etravirine and Raltegravir

Three posters at CROI 2015 described pharmacokinetics of antiretrovirals in pregnancy for rilpivirine, etravirine and raltegravir. None of the studies suggested that dose adjustment is required.

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IDWeek

HIV Drug Development Pipeline Update, Fall 2014 Edition

HIV treatment remains far from perfect, and there are still seats at the table available for improved antiretrovirals. Paul Sax, M.D., provides an update on several of the most noteworthy candidates currently in development.

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IDWeek

What's Hot in HIV Treatment

Here’s a recap of the biggest developments in HIV treatment over the past year, as well as a look at what’s to come.

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News

Dual Therapy With Etravirine and Raltegravir

Researchers in Barcelona, Spain, reported results from a pilot study where volunteers who were taking ART were screened and then recruited. Once in the study their regimens were changed to the following combination of just two drugs:

etravirine (Int...

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News

Pharmacokinetics of Etravirine With Once-Daily and Twice-Daily Dosing

A pharmacokinetics and pharmacodynamic analysis from a randomised study of etravirine in treatment-naive patients was published in the May/June edition of Clinical HIV Trials supporting once-daily dosing.1

This was an analysis from a double blind 48...

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News

Darunavir/Ritonavir and Etravirine as a Prevention Method Is Biologically Plausible

A pharmacokinetic study suggests that ritonavir-boosted darunavir (Prezista) and etravirine (Intelence) achieve high concentrations in semen and rectal tissue, and could therefore help avert HIV transmission and infection, especially in gay men. Conc...

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News

Intelence Now for Kids Ages 6 and Older

The HIV drug Intelence (etravirine) received approval from the Food and Drug Administration (FDA) for use by children ages six to 18 weighing at least 35 pounds, who have previous anti-HIV treatment experience. This includes children whose virus has ...

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News

Etravirine 200-mg Formulation Available in UK

On 17 January 2012, Janssen announced the launch of a 200 mg formulation of the NNRTI etravirine (Intelence).

The recommended oral dose of 200 mg etravirine is one tablet taken twice daily following a meal. The previous formulation required 2 x 100 ...

ICAAC HIV Poster Roundup #1: Clinically Relevant Findings Img
News

ICAAC HIV Poster Roundup #1: Clinically Relevant Findings

Here's a quick sampling of some of the more noteworthy HIV-related posters presented at a major research conference last week. Topics covered include a surprisingly high frequency of people quitting Atripla due to side effects; the decline of multidr...