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Single-Tablet HIV Regimen Containing Tenofovir Alafenamide Improves Bone and Kidney Safety Img

Single-Tablet HIV Regimen Containing Tenofovir Alafenamide Improves Bone and Kidney Safety

A new single-tablet HIV regimen containing tenofovir alafenamide (TAF) offered better bone and kidney safety, according to a study presented at ICAAC/ICC 2015.

Douglas Dieterich on Latest Hepatitis C Drugs (Video) Img

Douglas Dieterich on Latest Hepatitis C Drugs (Video)

Douglas Dieterich, M.D., who specializes in liver disease at Mount Sinai Hospital, discusses the new generation of medications against hepatitis C (HCV).

HIV and Cardiovascular Disease Img

HIV and Cardiovascular Disease

This year at CROI, there were over 30 abstracts on cardiovascular disease and HIV, which is a noticeable increase from prior years. Here's a recap of some of those studies.

CROI 2015: HIV Metabolic Issues Panel (Video) Img

CROI 2015: HIV Metabolic Issues Panel (Video)

Handling metabolic issues in HIV-positive patients requires a "multifactorial solution particularly emphasizing lifestyle modification."

CROI 2015: The (Lack of) Response to the Ebola Epidemic (Video) Img

CROI 2015: The (Lack of) Response to the Ebola Epidemic (Video)

With the deaths of 500 health care workers in West Africa due to Ebola, the epidemic has brought on a public health emergency in a region that already has a shortage of care providers and resources.

Varenicline (Chantix) Helps HIV-Positive Individuals Quit Smoking but Overall Success Rates Low Img

Varenicline (Chantix) Helps HIV-Positive Individuals Quit Smoking but Overall Success Rates Low

The use of varenicline (Chantix) appears to be relatively safe in people living with HIV, and when combined with counseling, could significantly increase the number who are able to quit smoking, according to a CROI 2015 study.

Tenofovir Alafenamide (TAF) Gentler on the Bones and Kidneys Img

Tenofovir Alafenamide (TAF) Gentler on the Bones and Kidneys

The new formulation of tenofovir, tenofovir alafenamide (TAF), was associated with less harm to bones and kidneys than the older formulation, tenofovir disoproxil fumarate (TDF, Viread).

Curing Hepatitis C Virus in HIV-Coinfected Patients: Mission Accomplished Img

Curing Hepatitis C Virus in HIV-Coinfected Patients: Mission Accomplished

"Mission Accomplished," the title given by CROI 2015 organizers for the session on hepatitis C (HCV) treatment, was premonitional. Two big phase-3 studies in HIV/HCV coinfected individuals were presented.

In the ION-4 study, 335 patients received tw...

Fat Gains After Starting HIV Treatment Associated With High Viral Loads Img

Fat Gains After Starting HIV Treatment Associated With High Viral Loads

Having a high viral load when starting treatment was most consistently associated with body composition changes after starting antiretroviral therapy.

High Cure Rates in HIV/HCV Coinfected Patients Taking Ledipasvir/Sofosbuvir Img

High Cure Rates in HIV/HCV Coinfected Patients Taking Ledipasvir/Sofosbuvir

Results from a study of 335 HCV/HIV coinfected patients showed a cure rate of 96%, offering compelling evidence that coinfected persons can be treated for hepatitis C with a once-daily regimen.