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Latest by Treatment Action Group

Undetectable Is Not Always Enough: Immunologic Nonresponders Face Increased Risk of Illness, but Lack Therapeutic Options Img

Undetectable Is Not Always Enough: Immunologic Nonresponders Face Increased Risk of Illness, but Lack Therapeutic Options

What is there to do with the small subset of positive people on treatment -- called immunologic nonresponders -- who reach undetectable but don't get a healthy boost in their CD4 count?

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News Analysis

Preparing for Generics: The Push for Affordable HIV Treatment Doesn't End With Patent Expirations

The United States is on course for some much-needed economic relief from the crippling cost of HIV treatment, with the anticipated arrival of generic versions of guidelines-preferred antiretrovirals. However, much preparation is required to maximize...

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News

The "G" Word: Gilead's Greed Gives Rise to a Slew of Advocacy Priorities

Activists are decrying Gilead's refusal to continue codeveloping a winning HCV drug combination with Bristol-Myers Squibb (BMS), opting instead to focus on co-formulations of its own promising agents. While a high-level petition continues to circulat...

Razing the House of Cards: The Discovery of HAART and the Push for Evidence-Based HIV Treatment Img

Razing the House of Cards: The Discovery of HAART and the Push for Evidence-Based HIV Treatment

This is the third in a series looking back at the first two decades of TAG's work to speed up AIDS research. In Part I: TAG's early campaigns to reform the National Institutes of Health (NIH) AIDS research, boost the federal budget, and revitalize HI...

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Can a Route to Broadly Neutralizing Antibodies Be Traced?

In recent years, new technologies have facilitated the discovery of an expanding number of antibodies capable of neutralizing a broad array of primary HIV isolates from different clades. As covered previously on the blog, these broadly neutralizing a...

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CMV Vector Vaccination Leads to Apparent Clearance of SIV Infection

Louis Picker from the Vaccine and Gene Therapy Institute at Oregon Health & Science University gave an update on results obtained in macaques with a CMV-based vaccine against SIV (abstract, webcast -- fourth in session). As Picker has shown in publis...

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Gene Modification of Virus-Specific CD4 T Cells

Patrick Younan from the Fred Hutchinson Cancer Research Center delivered an interesting talk about transplantation of gene-modified stem cells in pigtailed macaques (abstract, webcast -- third in session). The experiment used lentiviral vectors to de...

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Gastrointestinal

Probiotic/Prebiotic Supplement Combination Shows Benefits in SIV-Infected Pigtailed Macaques

Over the years, a number of small studies have been published suggesting that there might be benefits associated with probiotic and/or prebiotic supplementation in people with HIV infection. Probiotics typically comprise live microbes that play a key...

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Children (Ages 0-17)

Report of a Functional Cure in an HIV-Infected Infant

On Monday March 4th at the Conference on Retroviruses and Opportunistic Infections (CROI) in Atlanta, details were presented on a case of a potential "functional cure" of HIV infection in an infant. The story has already broken widely in the media du...

Australian AIDS Cure Claim Leads to a Maelstrom of Hype and Misinformation Img
News

Australian AIDS Cure Claim Leads to a Maelstrom of Hype and Misinformation

Last month, an Australian research center used the word "cure" in a press release promoting some early HIV study results. "The release spawned a maelstrom of misleading media coverage that has continued to swirl for weeks afterward," reports Richard ...