Latest by Polly Clayden
A report from the PROMISE study showed no adverse bone mineral effect, linked to maternal tenofovir disoproxil fumarate (TDF), in exposed infants.
Physiologically based pharmacokinetic modeling can help predict dosing strategies for long-acting antiretrovirals, according to data presented at CROI 2016.
Population modelling and pharmacokinetic simulations shown at CROI 2016 predicted dosing regimens to achieve target nevirapine treatment concentrations in term and late preterm infants.
Multiple dosing with doravirine does not change the plasma pharmacokinetics of a single dose of ethinyl estradiol or levonorgestrel to a clinically important extent, according to data shown at the 6th International Workshop on HIV and Women.
No Increased Risk of Birth Defects With Darunavir: Findings From the Antiretroviral Pregnancy Registry
The Antiretroviral Pregnancy Registry found no apparent increase in the frequency of specific birth defects with first trimester darunavir exposure.
Dolutegravir (DTG) is widely predicted to both provide better antiretroviral options for low-income countries and reduce the cost of global ART. But a number of steps need to happen before DTG is widely available and recommended for all populations....
Low- and middle-income countries with adult HIV prevalence less than 5% had significantly lower rates of treatment coverage in adults, pregnant women and children than those with higher prevalence.
Dolutegravir is safe and effective in children age 6-12 years, according to results presented at CROI 2016.
The introduction of three new antiretrovirals into treatment programmes in low- and middle-income countries -- tenofovir alafenamide fumarate (TAF), low-dose efavirenz (Sustiva, Stocrin) and dolutegravir (Tivicay, DTG) -- could represent over $3 bill...
Analysis of national treatment cascades showed huge variation in achieving UNAIDS 90-90-90 targets. The proportion of HIV positive people with undetectable viral load ranged from 68% in Switzerland to 9% in Russia. No country analysed met the UNAIDS ...