https://www.thebodypro.com/author/pablo-tebas

Pablo Tebas, M.D.

Latest by Pablo Tebas, M.D.

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Cardiovascular

Cardiovascular Risk and Antiretroviral Therapy: New Research on Epidemiology, Pathogenesis and Treatment

Introduction

The use of highly active antiretroviral therapy (HAART) regimens has markedly improved the long-term prognosis of people living with HIV infection. However, HIV disease and its treatment are associated with metabolic complications, incl...

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No Difference Seen in Resistance Profiles of Emtricitabine and Lamivudine

Lamivudine (3TC, Epivir) and emtricitabine (FTC, Emtriva) are extremely similar drugs. In fact, emtricitabine is lamivudine with one fluorine in one of the rings of the product.

As you can see, emtricitabine (left) looks awfully similar to lamivudin...

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Sequencing and 2 of the Most Popular Backbone Regimens

One of the most critical questions concerning antiretroviral therapy nowadays is how to best sequence drugs so that down the road patients will have more treatment options if their regimen should fail.

Currently the 2 most popular nucleoside backbon...

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Safety and Pharmacokinetic Data for 640385, a New Protease Inhibitor in Development

In July 2003, during the 2nd International AIDS Society Conference on Pathogenesis and Treatment, which was held in Paris, France,1 data were presented about the in vitro anti-HIV activity of a new protease inhibitor (PI) called 640385 (also known as...

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Cardiovascular

HIV-Infected Patients Have Multiple Risk Factors for Cardiovascular Disease

It is difficult to ignore data from prospective studies that involve over 1,000 patients. Some of the data might already be known, but having such a large sample size makes any conclusion almost definitive.

CPCRA is one of the large National Institu...

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Lipodystrophy/Body Fat

Predicting Lipoatrophy After Treatment Initiation

I liked this study. Mustafa Noor and the Bristol-Myers Squibb (BMS) group did a post-hoc analysis of a recent, large, randomized trial that compared the use of the currently available formulation of stavudine (d4T, Zerit) and stavudine extended relea...

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Lipodystrophy/Body Fat

Retrovirus 2003: Management of Metabolic Complications

During the last few years, the Retrovirus poster area, typically devoted to opportunistic infections, has been losing ground and shrinking, while the new, uncharted territory of metabolic complications of HIV infection and its treatment has grown big...

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Lipodystrophy/Body Fat

Improvements in Body Fat and Mitochondrial DNA Levels Are Accompanied by Decreased Adipose Tissue Cell Apoptosis After Replacement of Stavudine Therapy With Either Abacavir or Zidovudine

Improvements in Body Fat and Mitochondrial (Mt) DNA Levels Are Accompanied by Decreased Adipose Tissue Cell Apoptosis After Replacement of Stavudine (d4T) Therapy With Either Abacavir (ABC) or Zidovudine (ZDV) (Poster 728) Authored by K. Thomps...

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News

Effect of Amprenavir Hypersusceptibility on the Response to APV/Ritonavir-Based Therapy in ART-Experienced Adults Selected by Baseline Susceptibility (ESS40006): 24-Week Data

Effect of Amprenavir (APV) Hypersusceptibility on the Response to APV/Ritonavir (RTV)-Based Therapy in ART-Experienced Adults Selected by Baseline Susceptibility (ESS40006): 24-Week Data (Oral 143) Authored by R. Schooley, R. Haubrich, M. Thomp...

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Neurocognitive

HIV-Associated Neuromuscular Weakness Syndrome

HIV-Associated Neuromuscular Weakness Syndrome (Oral 87) Authored by D. Simpson, L. Estanislao, K. Marcus, M. Truffa, J. McArthur, B. Lucey, D. Dorfman, R. Naismith, I. Guerrero, J. Mendez, T. Lonergan, Y. Landau, M. Harris, J. Montaner, D. Cli...