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Latest by Bob Huff

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Features

HIV and Host Genetics: Complexity and Contradiction

I vividly remember the moment I understood how complex the life cycle of HIV must be and how difficult it could become to find a cure. During a press briefing at the 1989 International Conference on AIDS in Montreal, Professor Jay Levy, of the Univer...

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Gene Therapy: The Ultimate Fusion Blocker?

If the daily grind of subcutaneous injection of T-20 (Fuzeon) has got you down, why not let your T-cells make their own -- with gene therapy? Dorothee von Laer and Marc Egelhofer from Georg-Speyer-Haus in Germany and colleagues recently reported on p...

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Out of the Lab: A New Target and a New Agent From Gilead

This space reviews early laboratory findings from the Journal of Virology that shows scientists at work uncovering new ways to think about -- and ultimately beat the virus.

Betting on Betulinic Acid

In the January issue of the Journal of Virology, ...

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T-1249 Trial Suspended: Formulation Woes Blamed

As the New Year began, Roche and Trimeris announced that they had decided to halt further development of their experimental entry inhibitor, T-1249. The drug was a follow-on to T-20 (enfuvirtide, Fuzeon), the first-of-its-kind fusion inhibitor that r...

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One for the Blipper

You can be a "blipper" and still be chipper, suggests a study in the November 2003 issue of the Journal of Virology by Michele Di Mascio and her colleagues from the Los Alamos National Laboratory and the Aaron Diamond AIDS Research Center in New York...

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Paying for Life: The Issues Behind Drug Pricing

The Increasing Cost of U.S. Health Care Sorry, You’re Not on the List Why Is Price a Problem? Risky Business: The Case of T-20 Have I Got a Deal for You! The Best Is Not Good Enough Drug Pricing Terms Other Factors Affecting Price D...

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Hepatitis C

HCV Snapshots: Macro to Micro

HCV Prevalence in Europe Tracked

The enormously productive EuroSIDA study has reported on the prevalence of HCV in the cohort and on the effect that hepatitis C infection has on response to HAART. At the 9th European AIDS Conference in Warsaw, Polan...

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Tuberculosis

The Burden of Disease: HIV, TB, Malaria and Hepatitis

The "S" in AIDS stands for "syndrome," which refers to a pattern of illness proceeding from the immune deficiency that develops in the years after a person becomes infected with HIV: the human immunodeficiency virus. Many people have pointed out the ...

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Vaccinate to Prevent Hepatitis B

Susan Goldstein and colleagues from the Centers for Disease Control (CDC) have projected that if everyone born in 2000 were considered as a single cohort, and none were vaccinated for HBV, over their lifetimes they would experience 64.8 million HBV i...

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Tuberculosis

Tuberculosis Treatment Evolves

Over the past 50 years, and without any significant advances in the past 30 years, a number of fairly reliable medicines have been developed that effectively treat tuberculosis -- as long as they are consistently and correctly taken. But simply knowi...