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Alan Franciscus

Latest by Alan Franciscus

Evaluation of Instruments Used to Measure Hepatitis C Patient-Reported Symptoms Img
Hepatitis C

Evaluation of Instruments Used to Measure Hepatitis C Patient-Reported Symptoms

A study was conducted to evaluate the reliability and validity of several survey instruments that will be used in the PROP UP study to understand patient-reported symptoms before, during and after HCV treatment.

By Alan Franciscus for HCV Advocate
An Overview of Hepatitis C Transmission and Prevention Img
Hepatitis C

An Overview of Hepatitis C Transmission and Prevention

This fact sheet will describes transmission routes of hepatitis C and how to prevent its transmission.

By Alan Franciscus for HCV Advocate
Top 10 Hepatitis Stories of 2017 Img
Hepatitis C

Top 10 Hepatitis Stories of 2017

Every year there is always a lot of noteworthy news and information about hepatitis C, and the trend continued in 2017.

By Alan Franciscus for HCV Advocate
Hepatitis C in Prisons Img
Hepatitis C

Hepatitis C in Prisons

"Like it or not, if we are ever going to eliminate hepatitis C, we are going to have to test and treat prisoners," Alan Franciscus writes.

By Alan Franciscus for HCV Advocate
Hepatitis C Drug News: Odalasvir + AL-335 + Simeprevir Img
Hepatitis C

Hepatitis C Drug News: Odalasvir + AL-335 + Simeprevir

Phase 2a results were announced in a study to understand the safety and to determine an effective dose of the combination of odalasvir, AL-335 with and without simeprevir to treat HCV genotype 1 treatment-naive patients.

By Alan Franciscus for HCV Advocate
Effectiveness of Sofosbuvir, Ledipasvir/Sofosbuvir, or Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir Regimens for Treatment of Patients With Hepatitis C in the Veterans Affairs National Health Care System Img
Hepatitis C

Effectiveness of Sofosbuvir, Ledipasvir/Sofosbuvir, or Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir Regimens for Treatment of Patients With Hepatitis C in the Veterans Affairs National Health Care System

"The Veterans Affairs Healthcare system is a perfect place to test for 'real world' results," Alan Franciscus writes. "How do the direct-acting antiviral drugs work in a 'real world' setting as opposed to clinical trials?"

By Alan Franciscus for HCV Advocate
Hepatitis C Drug News: 3-Week Response-Guided Therapy Img
Hepatitis C

Hepatitis C Drug News: 3-Week Response-Guided Therapy

An important study was recently published in Lancet Gastroenterology & Hepatology holds the promise of changing the way that people with hepatitis C are treated.

By Alan Franciscus for HCV Advocate
Consequences of Inaccurate Hepatitis C Virus Genotyping on the Costs of Prescription of Direct Antiviral Agents in an Italian District Img
Hepatitis C

Consequences of Inaccurate Hepatitis C Virus Genotyping on the Costs of Prescription of Direct Antiviral Agents in an Italian District

Researchers conducted a study to analyze commercial hepatitis C genotype/subtype assays to understand the cost-effectiveness of potential errors in the assays.

By Alan Franciscus for HCV Advocate
5 HCV Genotypes Img
Hepatitis C

5 HCV Genotypes

There is a 30% to 35% difference in the genetic make-up of the nucleotide sites of the hepatitis C virus that is used to classify the different genotypes. This viral diversity is what makes it so difficult to develop one drug to treat all of the geno...

By Alan Franciscus for HCV Advocate
New Viral Hepatitis Numbers From the CDC Img
Hepatitis C

New Viral Hepatitis Numbers From the CDC

The Centers for Disease Control and Prevention (CDC) released new estimates on the acute and chronic cases of hepatitis A, B and C. The bad news is that the numbers for hepatitis C are continuing to rise.

By Alan Franciscus for HCV Advocate