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A Clinical Overview of Amdoxovir

Other Names: AMDX, DAPD, prodrug of DXG Drug Class: Nucleoside Reverse Transcriptase Inhibitors Molecular Formula: C9 H12 N6 O3 Registry Number: 145514-04-1 (CAS) Chemical Name: [(2R,4R)-4-(2,6-diaminopurin-9-yl)-1,3-dioxolan-2-yl]methanol Chemical...

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A Clinical Overview of AMD-070

Other Names: AMD-11070 Drug Class: Entry and Fusion Inhibitors Molecular Formula: C21 H27 N5 Registry Number: 558447-26-0 (CAS) Chemical Name: N'-(1H-benzimidazol-2-ylmethyl)-N'-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine Chemical Class: Benz...

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A Clinical Overview of Elvitegravir

Other Names: EVG, GS-9137, JTK-303 Drug Class: Integrase Inhibitors Molecular Formula: C23 H23 Cl F N O5 Registry Number: 697761-98-1 (CAS) Chemical Name: 6-[(3-chloro-2-fluoro-phenyl)methyl]-1-[(1S)-1-(hydroxymethyl)-2-methyl-propyl]-7-methoxy-4...

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A Clinical Overview of Dolutegravir

Other Names: DTG, GSK1349572, S/GSK1349572 Drug Class: Integrase Inhibitors Molecular Formula: C20 H19 F2 N3 O5 Registry Number: 1051375-16-6 (CAS) Chemical Name: 2H-Pyrido(1',2':4,5)pyrazino(2,1-b)(1,3)oxazine-9-carboxamide, N-((2,4-difluorophenyl)m...

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A Clinical Overview of S/GSK1265744

Other Names: GSK-1265744, GSK1265744, S-265744 Drug Class: Integrase Inhibitors Molecular Formula: C19 H17 F2 N3 O5 Registry Number: 1051375-10-0 (CAS) Company: ViiV Healthcare Phase of Development: IIb Molecular Weight: 405.3553 (Compound details ob...

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A Clinical Overview of Lersivirine

Other Names: UK-453,061 Drug Class: Non-nucleoside Reverse Transcriptase Inhibitors Molecular Formula: C17 H18 N4 O2 Registry Number: 473921-12-9 (CAS) Chemical Name: 5-[3,5-diethyl-1-(2-hydroxyethyl)pyrazol-4-yl]oxybenzene-1,3-dicarbonitrile Compa...

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A Clinical Overview of Tenofovir Alafenamide

Other Names: GS-7340, TAF, prodrug of tenofovir, tenofovir alafenamide fumarate Drug Class: Nucleoside Reverse Transcriptase Inhibitors Molecular Formula: C21 H29 N6 O5 P Registry Number: 379270-37-8 (CAS) Chemical Name: isopropyl (2S)-2-[[[(1R)-2...

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A Clinical Overview of Ibalizumab

Other Names: Hu5A8, TMB-355, TNX-355 Drug Class: Entry and Fusion Inhibitors Registry Number: 680188-33-4 (CAS) Chemical Name: Immunoglobulin G4, anti-(human CD4 (antigen)) (human-mouse monoclonal 5A8 γ4-chain), disulfide with human-mouse monoclonal ...

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A Clinical Overview of Elvucitabine

Other Names: ACH-126443, L-F-D4C Drug Class: Nucleoside Reverse Transcriptase Inhibitors Molecular Formula: C9 H10 F N3 O3 Registry Number: 181785-84-2 (CAS) Chemical Name: 4-amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimid...

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A Clinical Overview of INCB-9471

Other Names: INCB 9471, INCB-009471 Drug Class: Entry and Fusion Inhibitors Molecular Formula: C30 H40 F3 N5 O2 Registry Number: 925701-76-4 (CAS) Chemical Name: (4,6-dimethylpyrimidin-5-yl)-[4-[(3S,4R)-4-[(2R)-2-ethoxy-5-(trifluoromethyl)indan-1-...