https://www.thebodypro.com/article/two-drug-pill-before-and-after-sex-prevents-hiv-in
PrEP (HIV Pre-Exposure Prophylaxis)Men Who Have Sex With Men

Two-Drug Pill Before and After Sex Prevents HIV Infection in Gay Men

    Timing of PrEP Before and After Sex
    Timing of PrEP Before and After Sex Figure 1. Participants in a pre-exposure prophylaxis (PrEP) trial comparing TDF/FTC (Truvada) with a look-alike dummy pill aimed to take two pills 2 to 24 hours before sex, one pill 24 hours after the first two pills, and one pill 24 hours after the third pill.
    HIV Infection Rate With PreP Pill Versus Placebo (Dummy Pill)
    HIV Infection Rate With PreP Pill Versus Placebo (Dummy Pill) Figure 2. Taking two PrEP pills before sex and two PrEP pills after sex dramatically lowered the HIV infection rate in gay men who had frequent anal sex without a condom. Fourteen of 201 men assigned to take placebo versus 2 of 199 assigned to PrEP got infected. But the 2 men who got infected in the PrEP group were not taking their pills.
    This study of 400 men without HIV infection showed that taking two PrEP pills in the 24 hours before sex and two PrEP pills after sex lowered the risk of HIV infection 86%.
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    The Center for AIDS Information & Advocacy

    The Center for AIDS Information & Advocacy