Liver Transplant Does Not Increase HIV Reservoir in Virally Suppressed Recipients

Barbara Jungwirth

This research supports current HIV treatment recommendations that include dolutegravir as a preferred drug for those who are of childbearing potential, trying to conceive, or pregnant.

A mother kisses her newborn baby’s head while holding him in the hospital.

Study Bite: DTG Not Associated With Neural Tube Defects in U.S.

Dolutegravir Neural Tube Defects

Dolutegravir Not Associated With Neural Tube Defects in Large U.S. Study

Aug. 22, 2019: Links between thiamine deficiency and cognitive issues; HIV in cerebrospinal fluid and neurocognitive impairment; frailty, depression, and symptomatic cognitive issues; alcohol consumption and HIV disease progression.

This Week in HIV Research: Braining Bad

New findings out of Chicago suggest that injectable long-acting HIV treatment will be acceptable to a diverse group of people with HIV.

Injectable LA-ART Satisfaction Is High in Urban U.S. HIV Clinic

Long-Acting ART

Real-World Study Finds High Satisfaction With Injectable Long-Acting Cabotegravir/Rilpivirine in Urban Clinic

In this cohort of men with HIV in Italy, the traditional risk factors for diabetes were confirmed, while integrase inhibitors were not implicated.

Diabetes equipment and a stethoscope rest on a clipboard

Study Bite: INSTIs Did Not Increase Diabetes Among Men With HIV

Integrase Inhibitors Did Not Increase Diabetes Risk Among Italian Men Living With HIV

Adverse Events and Comorbidities in People Living With HIV

Adverse Events and Comorbidities in People Living With HIV - TheBodyPro

Adverse Events & Comorbidities

This Week in HIV Research

Susan Yox, RN, Ed.D.

Providing Quality HIV Care

We summarize several recently published studies that, together, offer new insights into practical guidance for HIV clinical care.

Research Roundup: Women and HIV

Study Recaps

A new analysis supports the use of race-neutral pulmonary function reference equations for people living with HIV.

No Need to Adjust for Race When Analyzing Pulmonary Function

Cardiovascular Health

Racial Adjustment Not Needed for Pulmonary Function Analysis in People With HIV, Says U.S. Study

HIV and Mental Health

Authors of a new position paper outline clinical, research, and public health recommendations to improve brain health in people aging with HIV.

Next Steps for Improving Neurocognition in Older People With HIV

Neurocognitive Health

Next Steps for Improving Neurocognition Among Older People With HIV: More Research, Continuum Enhancements, Knowledge Hub

HIV Care Continuum

A large study reinforces the impact of substance use disorders on viral load in people with HIV who are taking antiretroviral therapy.

Substance Use and Sustained Viral Suppression in HIV

Viral Load Impact

Substance Use Disorders Associated With Lower Sustained Viral Suppression in People With HIV

Antiretroviral Therapy

In this real-world study, researchers concluded that high BMI need not be an automatic disqualifier for people who would otherwise consider LA-CAB/RPV.

Long-Acting Injectable ART Effective in People With High BMI

Overweight Patients

Study Finds Long-Acting Injectable HIV Treatment Effective in People With High BMI

A viral load that remained near 200 copies/mL emerged as a risk factor for eventual virologic failure among people on antiretroviral therapy in a Swiss study.

Virologic Failure Risk Following “High Low-Level Viremia”

Loss of Suppression

Persistent Viral Load Between 150 and 200 Associated With Later Virologic Failure in Swiss Study

Only half of screening-eligible participants living with HIV received anal cancer screenings, according to a review of data from a pair of large, urban HIV clinics in the U.S.

Anal Cancer Screening Remains Underused in Men With HIV

Cancer and HIV

Anal Cancer Screening Is Successful, but Still Underused, in Men Living With HIV

HIV Care and Services Outside the US

Care & Services Outside the U.S.

Not there yet: While goals were exceeded for initiating PrEP in countries supported by CDC, the world is still far behind on reaching the overall target for people using PrEP.

CDC Reports Progress on Meeting Global PrEP Goals

PrEP Uptake

CDC Reports Progress and Potential Shortfalls in Meeting Global PrEP Access Goals

While overall cancer incidence in people with HIV has been declining, a large U.S. study finds differences among various subgroups.

Disparities in Cancer Trends Among People With HIV

Large U.S. Study Explores Disparities in Cancer Trends Among People Living With HIV

Transitioning women with HIV to integrase inhibitors before (or more than three years after) menopause may minimize the impact on waist circumference and body mass.

Consider Menopausal Stage When Switching to Integrase Inhibitors

Body Weight

Consider Menopausal Stage When Switching Middle-Aged Women to Integrase Inhibitors, U.S. Study Suggests

HIV Epidemiology

Epidemiology

A recent study found no difference in alcohol use by HIV status, but revealed a considerable number of women whose phosphatidylethanol levels suggested they drank more than they reported.

Underreporting of Alcohol Use in Women With vs. Without HIV

Substance Use

Underreporting of Alcohol Use by Women Is Common, but Does Not Differ by HIV Serostatus, in San Francisco Study

In people living with HIV and hepatitis C, hepatic steatosis incidence did not decline after successful HCV treatment, indicating the need for continued liver health monitoring, a Canadian study reports.

Pre- vs. Post-Treatment Steatosis in People With HIV and HCV

Hepatitis C Coinfection

Study Finds No Drop in Hepatic Steatosis Risk After HCV Treatment in People With HIV/HCV Coinfection

Latently infected HIV remained steady in virally suppressed PLWH after they received a liver transplant, regardless of the donor’s HIV status or viral load.

Liver transplant surgery in a surgical suite.

Study Bite: Liver Transplant Does Not Increase HIV Reservoir

HIV Education and Risk Management

Education & Risk Management

This study found a notable level of undertreatment for hospitalized people with opioid use disorder—a gap that persisted from inpatient admission to outpatient care linkage at four major medical centers in the United States. 

An emergency room doctor asks a patient questions.

Study Bite: IDU-Related Hospitalizations Often Don't Lead to Substance Use Treatment

Substance Use Treatment Initiation Rare Following Injection Drug Use-Related Hospitalizations in U.S. Study

A modeling study found significant promise in a combination of immediate antiretroviral treatment and guideline-based follow-up focused specifically on Black people living with HIV.

A doctor shakes the hand of a patient as she meets him for the first time.

Study Bite: Focused Interventions for Black People Can Reverse HIV Mortality Gap

Focusing Interventions on Black People Can Reverse the Racial HIV Mortality Gap in the United States, Modeling Study Finds

While overall awareness was high, PrEP usage was just 5%—and awareness was actually lower among women reporting inconsistent condom use.

A health care professional discusses treatment plans with a patient.

Liver Transplant Does Not Increase HIV Reservoir in Virally Suppressed Recipients

About This Study

Key Research Findings

Discussion Highlights and Implications for Practice