Open Clinical Trials

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U.S. HIV/AIDS Trial Databases

AIDSinfo (Regularly Updated)
An extensive, searchable list of trials, provided by the U.S. Department of Health and Human Services.
Browse for Clinical Trials by Category (Regularly Updated)
Alternative/Complementary Medicine; HIV Acute/Early Infection; HIV and anal dysplasia; HIV and cervical dysplasia; HIV and HPV; HIV and Pregnancy; HIV Prevention (mother-child transmission, behavior, vaccines, etc.); HIV Resistance/Resistance Testing; HIV Treatment Experienced; HIV Treatment Interruption; HIV Treatment Naive (little or no prior treatment); HIV Vaccines; Lipodystrophy/Lipoatrophy; Neuropathy; Observational Trials; Pediatric HIV; Post Exposure to HIV; General Search.
Complementary Therapy Trials for People With HIV (Regularly Updated)
Trials throughout the U.S.

NIAID's Clinical Trials Recruitment Database (Regularly Updated)
Provides information on experimental-treatment and vaccine studies conducted or supported by the National Institute of Allergy and Infectious Diseases.
ACRIA TrialSearch
A national database of enrolling HIV/AIDS clinical trials. Searchable by treatment, condition, CD4 and viral load counts, age and location.
From AIDS Community Research Initiative of America

U.S. Non-HIV Trial Databases

CenterWatch Clinical Trials Listing Service (Regularly Updated)
A thorough listing of industry-sponsored enrolling trials (not HIV-specific), searchable or browseable by medical area.
Clinical Trials Supported by the National Eye Institute (Regularly Updated)
May be of interest to HIV-positive patients, particularly those with CMV retinitis or other vision-impairing conditions.
ClinicalTrials.gov (Regularly Updated)
Searchable (by keyword) database of all research studies (including those related to HIV/AIDS) being conducted/sponsored by the National Institutes of Health, other federal agencies or the pharmaceutical industry.
CRISP: Computer Retrieval of Information on Scientific Projects (Regularly Updated)
A searchable database of federally funded biomedical research projects conducted at universities, hospitals, and other research institutions.
National Cancer Institute: Clinical Trial Search (Regularly Updated)
A searchable database of open and closed cancer-related trials throughout the world.

Specific U.S. Nationwide Studies

ESPRIT: Interleukin Study (Regularly Updated)
A large-scale, randomized, international study of the effectiveness of IL-2 in HIV-positive people with CD4+ counts over 300.
The Neurologic AIDS Research Consortium (Regularly Updated)
The U.S. Military HIV Research Program (Regularly Updated)
Women's Interagency HIV Study (Regularly Updated)
A large, long-running, ongoing investigation of the clinical, laboratory and psychosocial aspects of HIV infection in women.
Penn Medicine Leads $45 Million NIH-Supported Trial to Study Testosterone Therapy in Older Men (November 2, 2009)
From Penn Medicine
Can Raltegravir Further Reduce Viral Load? (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
Maraviroc for CD4 Cell Recovery (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
Once-Daily Raltegravir for Treatment-Naive Patients (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
Rilpivirine (TMC278) for Treatment-Naive Patients (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
Vaginal Microbicides (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
Vicriviroc in People With Dual/Mixed-Tropic HIV (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients (April 15, 2008)
Novel nucleoside-sparing regimen designed to avoid risk of toxicity associated with nucleoside class of HIV drugs.
From Schering-Plough
Not Your Everyday Antiretroviral: KP-1461, an HIV DNA Killer (October 11, 2007)
In AIDS Treatment News, from AIDS Treatment News
Tibotec Therapeutics Announces Initiation of the Largest U.S. Clinical Study Examining HIV Treatment in Treatment-Experienced Adult Women (September 28, 2006)
From Tibotec Therapeutics

Trial Databases (Outside U.S.)

metaRegister of Controlled Trials (Regularly Updated)
A massive, searchable, global database of ongoing, randomized, controlled trials (Free registration is required to search the database).
Australian Clinical Studies (Regularly Updated)
Clinical Trials Currently Underway in Canada (Regularly Updated)
A listing provided by the Canadian HIV Trials Network.
IAVI Database of Preventive AIDS Vaccines in Human Trials (Regularly Updated)
A searchable, global database provided by the International AIDS Vaccine Initiative.

Specific Trials (Outside U.S.)

EuroSIDA: Impact of Antiretrovirals on HIV-Positive Europeans (Regularly Updated)
A very large, prospective, observational cohort study spanning the European continent.
SPARTAC Study (April 8, 2006)
Clinical trial underway in the United Kingdom examining whether short-term treatment in recently infected people can delay the start of long-term therapy.
From Medical Research Council Clinical Trials Unit

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