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BROWSE TOPICS IN CLINICAL MANAGEMENT:
Antiretroviral Therapy- Complications of HIV/HAART
- Research & Development
- Clinical Trials
- Quality of Life & Patient Care
Antiretroviral Therapy
HIV Drug-Drug Interactions
Overview
- Drug Interactions Among Antiretrovirals and Other Drugs: NNRTIs (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo - Drug Interactions Among Antiretrovirals and Other Drugs: NRTIs (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo - Drug Interactions Among Antiretrovirals and Other Drugs: PIs and Maraviroc (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo - Drugs That Should Not Be Used With PI, NNRTI , or CCR5 Antagonist Antiretrovirals (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo - Dosage Adjustments for ARV-ARV Drug Interactions (Adult Dosing) (July 2006)
From AIDS Education & Training Centers National Resource Center - Antiretroviral Medications and Oral Contraceptive Agents (2006)
A chapter from Clinical Manual for Management of the HIV-Infected Adult.
From AIDS Education & Training Centers National Resource Center - Drug Interactions and Anti-HIV Therapy (Summer 2005)
To read PDF, click here
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation - A Review of Interactions Between Natural Health Products and HIV Medications (April 2005)
A brief summary of a report in the International Journal of STD & AIDS.
From The Body PRO - Psychiatric and HIV Medication Interactions (January 2005)
A chart outlining known interactions between psychiatric medications and NRTIs, NNRTIs and protease inhibitors.
To read PDF, click here
In Infectious Diseases in Corrections Report, from Brown Medical School - Drug Interactions Fact Sheet (August 2004)
An exhaustive list of drug interactions.
To read PDF, click here
From Project Inform - Case Study: Drug-Drug Interactions Associated With the Use of Antiretroviral Therapy (March 2004)
In HEPP Report, from Brown Medical School - Clinically Significant Drug Interactions Associated With Highly Active Antiretroviral Therapy (January 2004)
To read PDF, click here
In HEPP Report, from Brown Medical School - Risky Cocktails (April 2003)
A chart of interactions between alcohol/recreational drugs and HIV antiretrovirals.
In Survival News, from AIDS Survival Project - Methadone and HIV Medications: Drug Interactions (Winter 2002/2003)
To read PDF, click here
In STEP Perspective, from Seattle Treatment Education Project - The Effects of Club Drugs on HAART (December 2002)
To read PDF, click here
In IAPAC Monthly, from International Association of Physicians in AIDS Care - Pharmacology and Drug Interactions: A Progress Report (September 2002)
A report from the International AIDS Conference.
In Hopkins HIV Report - Drug Interactions: Ritonavir as PI Booster (July 2001)
From Project Inform - Drug-Drug Interactions With HIV-Related Medications (2006)
A chapter from Clinical Manual for Management of the HIV-Infected Adult.
From AIDS Education & Training Centers National Resource Center - Recreational Drugs and Antiretroviral Therapy (2006)
A chapter from Clinical Manual for Management of the HIV-Infected Adult.
From AIDS Education & Training Centers National Resource Center
Drug Interaction Research
- Drug Monitoring and Pharmacology: More Mixes Nixed By Concentration Preoccupations (August 2004)
Highlights from a CROI 2004 post-conference workshop on drug-drug interactions.
In TAGline, from Treatment Action Group - Tipranavir Reduces Concentrations of Other Protease Inhibitors (July 14, 2004)
In The XV International AIDS Conference, from The Body PRO - Tenofovir and Abacavir Do Not Interact in Patients on Triple-Nucleoside Regimens (July 13, 2004)
In The XV International AIDS Conference, from The Body PRO - Making Right Turns in the HIV Pharmacology Maze: 5th International Workshop on Clinical Pharmacology of HIV Therapy (July 2004)
Highlighted research on host factor relevance, new antiretrovirals and drug-drug interactions.
To read PDF, click here
In IAPAC Monthly, from International Association of Physicians in AIDS Care - Dosing Agenerase + Kaletra -- Trying to Juggle, Walk and Chew Gum All at the Same Time (March/April 2004)
A study presented at CROI 2004 bolsters support for the use of therapeutic drug monitoring to customize dosing.
In Positively Aware, from Test Positive Aware Network - Efavirenz May Reduce Blood Levels of Cholesterol Drugs (March/April 2004)
A study presented at CROI 2004 suggests an interaction between efavirenz and simvastatin (Zocor) or atorvastatin (Lipitor).
In Positively Aware, from Test Positive Aware Network - A Look at Tenofovir Drug-Drug Interactions (September 16, 2003)
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO - No PK Interaction Seen Between FTC and AZT or Tenofovir (September 16, 2003)
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO - Pharmacokinetic Interactions of 908 (September 16, 2003)
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO - No Interactions Between Tipranavir/Ritonavir and Efavirenz, Tenofovir and AZT (July 14, 2003)
In The 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment, from The Body PRO - HIV-Positive Man Dies of Kidney Failure and Lactic Acidosis Due to Tenofovir/ddI Interaction (April 8, 2003)
From aidsmap.com - Didanosine and Tenofovir DF Drug-Drug Interaction: Assessment of Didanosine Dose Reduction (February 12, 2003)
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO - Lack of Interaction Between Stavudine Extended-Release Formulation and Tenofovir Disoproxil Fumarate (February 12, 2003)
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO - Pharmacokinetic Parameters of Atazanavir/Ritonavir When Combined to Tenofovir in HIV Infected Patients With Multiple Treatment Failures: A Substudy of Puzzle2-ANRS 107 Trial (February 12, 2003)
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO - New Questions About an Old Combination -- ddI + d4T (January 2003)
To read PDF, click here
In Project Inform Perspective, from Project Inform - Tenofovir DF and Didanosine EC: Investigation of Pharmacokinetic Drug-Drug and Drug-Food Interactions (July 11, 2002)
In The XIV International AIDS Conference, from The Body PRO - Polypharmacy Problems: Drug Interactions in the Multi-Drug Therapy of HIV Infection (February 6, 2002)
In The PRN Notebook - Drug Interaction: Ritonavir and Fluticasone (November 2001)
Possible link found to Cushing's Syndrome.
In HIV Treatment ALERTS!, from The Center for AIDS - Ingrown Toenails Still a Possible Side Effect (November 2001)
Indinavir-ritonavir interaction is possible culprit.
In HIV Treatment ALERTS!, from The Center for AIDS - Lack of Clinically Relevant Drug-Drug Interactions Between Tenofovir DF and Efavirenz, Indinavir, Lamivudine and Lopinavir/Ritonavir in Healthy Subjects (October 29, 2001)
In 8th European Conference on Clinical Aspects and Treatment of HIV-Infection, from The Body PRO - Minor Interaction Between Efavirenz and Saquinavir When Combined With Small Doses of Ritonavir in a QD Regimen (October 28, 2001)
In 8th European Conference on Clinical Aspects and Treatment of HIV-Infection, from The Body PRO
Drug-Drug Interaction Tools
- Database of Antiretroviral Drug Interactions (Regularly Updated)
Search through this comprehensive, fully-referenced database of interactions involving at least one antiretroviral drug.
From HIV InSite - HIV-druginteractions.org: Online Resource on Drug Interactions (Regularly Updated)
Maintained by the University of Liverpool and geared toward healthcare professionals; features interactive charts for assessing the risks of interaction between protease inhibitors, NNRTIs and other drugs.
From University of Liverpool - HIV/AIDS Clinical Calculator (Regularly Updated)
Drug-drug interactions and medication daily scheduler.
From Medscape
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