Darunavir Matches, and in Some Patients Outperforms, Lopinavir/Ritonavir as Second-Line and Third-Line Treatment (July 25, 2007)
For the first time, a drug has been found that matches the potency of lopinavir/ritonavir in second-line and third-line patients, and which might potentially even outperform lopinavir/ritonavir in certain numbers of those patients. All without compromising safety and tolerability, and apparently without paying resistance consequences if virologic failure occurs. Edwin DeJesus, M.D., reports.
In 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, from TheBodyPRO.com
Tenofovir-Containing Regimens May Not Be the Best Option for Patients With Abnormal Baseline Renal Function (July 25, 2007)
Tenofovir-containing regimens may not be the best option for patients who already have an abnormal baseline renal function; however, for patients with an otherwise normal baseline renal function, who are not taking nephrotoxic agents or who do not have significant comorbid conditions that predispose them to renal insufficiency, routine renal monitoring, as we do for many other patients, should suffice before prescribing tenofovir.
In 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, from TheBodyPRO.com
Can HLA-B*5701 Testing Help Avoid Abacavir Hypersensitivity Reaction? (July 25, 2007)
Avoiding abacavir hypersensitivity reaction may be as easy as screening for the HLA-B*5701 allele in any HIV-infected, abacavir-naive patient for whom abacavir therapy is being considered. Graeme Moyle, M.D., reports.
In 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, from TheBodyPRO.com