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ICAAC/IDSA 2008 Newsroom
- New Developments in HIV/Hepatitis C Coinfection Management and Epidemiology (February 25, 2009)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Starting Therapy Earlier Found to Improve Survival (January/February 2009)
Study raises the implications of more testing, less transmission.
To read PDF, click here.
In Positively Aware, from Test Positive Aware Network
- HIV Treatment News From the 48th ICAAC (January/February 2009)
A round-up of reports.
To read PDF, click here.
In Positively Aware, from Test Positive Aware Network
- Efavirenz Significantly Reduces Levels of Some Oral Contraceptives (November/December 2008)
In HIV Treatment Bulletin, from HIV i-Base
- Study Shows People Can Safely Switch to Atripla (December 2008)
To read PDF, click here.
From Project Inform
- Switch to Viramune Safe for Some Who Can't Tolerate Sustiva (December 2008)
To read PDF, click here.
In Project Inform Perspective, from Project Inform
- Peculiar Type of KS Emerges in Healthier Individuals (November 7, 2008)
From Project Inform
- Some AIDS-Defining Conditions Now Diagnosed at Higher CD4s (November 6, 2008)
From Project Inform
- Evolving Options for First-Line Therapy: Highlights From ICAAC/IDSA 2008 (November 3, 2008)
David Wohl, M.D., explores the clinical importance of new data from a passel of head-to-head clinical trials in treatment-naive patients, including investigations of abacavir/lamivudine, atazanavir, darunavir, lopinavir/ritonavir, maraviroc, raltegravir and tenofovir/emtricitabine.
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Reappraising Key Issues in HIV Clinical Management: Highlights From ICAAC/IDSA 2008 (November 3, 2008)
Benjamin Young, M.D., Ph.D., leads an insightful discussion on new data regarding etravirine and raltegravir; a revisitation of the "when to start" question; alarming disparities in HIV care among U.S. women; and the clinical management of aging HIV-infected patients.
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- New AIDS Drug, New Abbott Rival (October 30, 2008)
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
- Superinfection More Common Than Expected Among Heterosexual Cohabiting Couples in Zambia, Small Study Finds (October 28, 2008)
Genetic screening of HIV strains reveals cases of HIV superinfection among two of 15 couples in a Zambian cohort. (An interview with Colleen Kraft, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- CD4+ Cell Count Decline in HIV-Infected Patients Is Growing More Rapid, Military Study Suggests (October 28, 2008)
A 20-year analysis of 2,000 U.S. military patient records appears to add credence to the argument that HIV has grown more virulent than it was during the early years of the epidemic. (An interview with Nancy Crum-Cianflone, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Smallpox Vaccine Safe in HIV-Infected Patients (October 28, 2008)
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
- Merck's Antiretroviral Isentress More Efficient in Suppressing HIV Among Untreated Patients (October 28, 2008)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
- Impact of Testosterone Levels on Bone Mineral Density May Be More Pronounced in HIV-Infected Patients (October 27, 2008)
A retrospective, controlled study of 237 patients finds that, among patients with low testosterone levels, those who are HIV infected have lower bone mineral density than those who are HIV uninfected. (An interview with Ranjani Raghunathan, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Continuous HAART Associated With Decreased Bone Mineral Density, SMART Substudy Finds (October 27, 2008)
In one of ICAAC/IDSA 2008's most talked-about studies, a SMART substudy suggests that participants who remained on HAART continuously experienced a significantly greater reduction in bone marrow density than patients on intermittent therapy. (An interview with Birgit Grund, Ph.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- ICAAC/IDSA 2008 Highlights: Joel Gallant, M.D., Recaps the Most Clinically Relevant Findings (October 27, 2008)
What are the findings presented at this conference that are most likely to impact everyday clinical practice for HIV health care providers? Dr. Gallant offers his expert perspective on ICAAC/IDSA 2008's most important research.
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body
- Hospitalization Risk Similar Between HAART Responders and Nonresponders for 90 Days After Starting Therapy (October 27, 2008)
The benefits of HAART initiation -- at least in terms of preventing or ameliorating illnesses that require hospitalization -- may not manifest themselves for up to three months, according to a sizeable study by Johns Hopkins University researchers. Women were more likely to be hospitalized than men, and choice of HAART regimen appeared to have no impact. (An interview with Stephen Berry, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- CASTLE Study Compares Reyataz to Kaletra (October 27, 2008)
From Project Inform
- Two Studies Look at Intelence (October 27, 2008)
From Project Inform
- Does Kaletra Monotherapy Work? Depends on Who You Ask (October 27, 2008)
Project Inform says the latest findings on lopinavir/ritonavir monotherapy are anything but positive.
From Project Inform
- Analysis of CASTLE Finds No Benefit for Once-Daily Dosing (October 27, 2008)
From Project Inform
- Long-Term Safety Study of Vicriviroc Presented (October 27, 2008)
From Project Inform
- Four Posters Add to Our Knowledge of Lexiva (October 27, 2008)
From Project Inform
- Patients on Tenofovir/Emtricitabine May Face Higher Bone Risk From Vitamin D Insufficiency (October 27, 2008)
A small study finds that, although vitamin D insufficiency is quite common among HIV-infected people, it may be a particular risk for patients receiving tenofovir/emtricitabine: These patients appear especially likely to have elevated parathyroid hormone levels, which has been associated with bone problems. (An interview with Kate Childs, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Diabetes Risk Appears Lower for HIV-Infected Patients Than Uninfected Patients (October 27, 2008)
A large, ongoing study of U.S. military veterans also suggests that the usual risk factors for diabetes, not HIV itself, are the main drivers of diabetes in HIV-infected people. (An interview with Adeel A. Butt, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Eric Daar, M.D., Summarizes Key Antiretroviral Trials (Patient Friendly) (October 27, 2008)
From atazanavir to fosamprenavir and from darunavir to raltegravir, several clinical trials were presented at ICAAC/IDSA 2008 that may shift the prescribing landscape for HIV clinicians. In this review geared toward the patient population, Dr. Daar provides a rundown of these noteworthy studies and explains their significance.
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body
- HAART Use Improves Hepatitis B Vaccine Response, Even at High CD4 Counts (October 27, 2008)
HIV-infected patients are approximately twice as likely to respond to hepatitis B vaccination if they are receiving antiretroviral therapy, regardless of their CD4+ cell count at the time of vaccination, according to a study by researchers with the U.S. military. (An interview with Michael Landrum, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Studies: Newer HIV Drugs More Tolerable for Many (October 27, 2008)
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
- Antiretroviral Treatment Should Start Earlier, Study Says (October 27, 2008)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
- Switch to Tenofovir/Emtricitabine From Abacavir/Lamivudine Appears to Halt Lipoatrophy: Gilead 934 Rollover (October 26, 2008)
In a prospective rollover study from the landmark Gilead 934 trial, patients who switched NRTI combinations ceased losing fat, maintained virologic suppression and exhibited no significant change in creatinine clearance or glomerular filtration rate. (An interview with Edwin DeJesus, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Switching From Combivir to Truvada Keeps HIV Undetectable, Improves Blood Fats, But Fails to Improve Limb Fat (October 26, 2008)
From Project Inform
- Results From Elvucitabine Study Unimpressive (October 26, 2008)
From Project Inform
- Study Supports Use of Isentress for First-Line Treatment (October 26, 2008)
From Project Inform
- HEAT: Virologic Failure Rates Similar (and Low), Emerging Resistance Uncommon on Abacavir/Lamivudine vs. Tenofovir/Emtricitabine (October 26, 2008)
The similarities between these two first-line nucleoside backbones is reiterated in a new examination of virologic failure data from the 96-week results of the HEAT study. (An interview with Benjamin Young, M.D., Ph.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Trend Toward Fewer AIDS-Defining Conditions Among Patients Receiving Raltegravir vs. Placebo (October 26, 2008)
A new examination of 48-week BENCHMRK data found a nearly twofold reduction in AIDS-defining events among patients on raltegravir, but the findings failed to reach statistical significance. Intriguingly, greater resistance did not appear to be a predictor of AIDS-defining events. (An interview with Joseph Eron Jr., M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- 96-Week ARTEMIS Data Indicate Darunavir Is Superior to Lopinavir in Naive Patients (October 26, 2008)
Following 48-week data that proved darunavir's non-inferiority to lopinavir, these new, even more encouraging 96-week data appear likely to solidify the drug's role in first-line therapy. (An interview with Tony Mills, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Crafting First-Line Regimens: So Easy a General Practitioner Could Do It? (October 26, 2008)
We may have more antiretrovirals to choose from than ever before, but selecting an initial HAART regimen today is often a choice between just two regimens, a new study indicates. The findings suggest it may be realistic for primary care physicians and general practitioners to shoulder more of the HIV care burden. (An interview with James McKinnell, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Study Shows Better Results From Vicriviroc When New Trofile Test Is Used (October 26, 2008)
From Project Inform
- Study Data Explain Raltegravir's Excellent Resistance Profile (October 26, 2008)
From Project Inform
- RDEA Study Supports Further Development of New NNRTI (October 26, 2008)
From Project Inform
- Study May Point Way Forward for Bevirimat (October 26, 2008)
From Project Inform
- Large Study Supports Earlier Treatment (October 26, 2008)
From Project Inform
- Starting HAART: Should 500 Become the New 350? (October 26, 2008)
Mari Kitahata, M.D., and Daniel Kuritzkes, M.D., discuss a 5,926-patient trial that found a 74% higher mortality risk among those who deferred HAART until their CD4 dropped below 350 rather than initiating when their CD4 was between 351 and 500. Dr. Kuritzkes also touches on new developments in HIV drug resistance.
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Meningococcal Vaccine Appears Safe in Youth With HIV (October 25, 2008)
From Project Inform
- Adding GM-CSF to Hepatitis B Vaccine Fails to Work (October 25, 2008)
From Project Inform
- Ensuring ADAPs Realize the Best Health Outcomes for All Eligibles (October 25, 2008)
From Project Inform
- Four Weeks of Therapy Enough to Prevent MTC Transmissions (October 25, 2008)
From Project Inform
- The Hidden Costs of Prior Authorization: Wasted Time and Medication Delays (October 25, 2008)
Insurers may save money by requiring prior authorization for medication access, but when it comes to HIV care, health care providers (and, as a result, their patients) are the ones who suffer, according to real-world observations of an Alabama HIV Clinic. (An interview with James Willig, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- African Americans With HIV Have Higher OI Rates and Hospital Mortality, but Lower HCV Rates, Than Whites, Hospital Survey Finds (October 25, 2008)
A massive, nationwide hospital survey reveals that black, hospitalized HIV-infected patients experience greater morbidity and mortality than their white counterparts -- but also appear less likely to be coinfected with hepatitis C. (An interview with Christine Oramasionwu, Pharm.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- CD4-Based ADAP Waiting Lists Can Save More Lives Than First-Come, First-Served Lists, Study Suggests (October 25, 2008)
ADAP waiting lists that determine enrollment priority based on a patient's CD4 count can ensure lower mortality rates than ADAP waiting lists that determine priority on a first-come, first-served basis, according to calculations by a team of Massachusetts researchers. (An interview with Benjamin Linas, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- HIV-Infected U.S. Women More Likely to Abort Pregnancy Than HIV-Uninfected Women (October 25, 2008)
Abortions were more common among pregnant, HIV-infected women receiving care at a major Mid-Atlantic clinic, despite findings that there was no greater risk of stillbirth and a lower risk of miscarriage. (An interview with Susan Matcha, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Many Black, HIV-Infected Women in Mississippi Are Lost to Care After Giving Birth (October 25, 2008)
The U.S. health care system has succeeded wonderfully at preventing mother-to-child HIV transmission. But is it failing to provide low-income, HIV-infected women with the care they need after they have given birth? (An interview with Aadia Rana, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO
- Ethnicity Does Matter When It Comes to Quality of HIV Care in United States, Survey Finds (October 25, 2008)
African-American and Hispanic-American female patients often feel that their culture or ethnicity impacts their HIV care -- so much so, in fact, that many end up switching HIV care providers because of communication problems, according to a nationwide survey. (An interview with Sally Hodder, M.D.)
In The 48th Annual ICAAC/IDSA 46th Annual Meeting, from The Body PRO