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1 September 2007

Volume 45, Number 5
Clinical Infectious Diseases 2007;45:654–657
1058-4838/2007/4505-0021$15.00
DOI: 10.1086/520652
HIV/AIDS BRIEF REPORT

Immunologic and Clinical Responses to Highly Active Antiretroviral Therapy in Patients with HIV Infection Aged >50 Years

Lise Cuzin,

Cyrille Delpierre,

Stéphane Gerard,

Patrice Massip, and

Bruno Marchou

Department of Infectious and Tropical Diseases, Hopital Purpan, Toulouse, France

We analyzed the effect of age on highly active antiretroviral therapy efficacy and tolerance in 639 patients with human immunodeficiency virus (HIV) infection (99 of whom were aged >50 years, and 540 of whom were aged <50 years). Late testing, which was more frequent in the older age group, was the only independent factor associated with immunologic and clinical evolution of infection. Age >50 years was associated with earlier treatment discontinuation.

Received 16 February 2007; accepted 1 May 2007; electronically published 19 July 2007.

Reprints or correspondence: Dr. Lise Cuzin, CISIH, Hopital Purpan, TSA 40031, 31059 Toulouse, Cedex 9, France ().

Cited by

Adena H Greenbaum, Lucy E Wilson, Jeanne C Keruly, Richard D Moore, Kelly A Gebo. (2008) Effect of age and HAART regimen on clinical response in an urban cohort of HIV-infected individuals. AIDS 22:17, 2331-2339
Online publication date: 1-Dec-2008.
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Kavita P. Bhavan, Vinay N. Kampalath, Edgar Turner Overton. (2008) The aging of the HIV epidemic. Current HIV/AIDS Reports 5:3, 150-158
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Benedetta Longo, Laura Camoni, Stefano Boros, Barbara Suligoi. (2008) Increasing Proportion of AIDS Diagnoses among Older Adults in Italy. AIDS Patient Care and STDs 22:5, 365-371
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