Immunologic and Clinical Responses to Highly Active Antiretroviral Therapy in Patients with HIV Infection Aged >50 Years
Department of Infectious and Tropical Diseases, Hopital Purpan, Toulouse, France
We analyzed the effect of age on highly active antiretroviral therapy efficacy and tolerance in 639 patients with human immunodeficiency virus (HIV) infection (99 of whom were aged >50 years, and 540 of whom were aged <50 years). Late testing, which was more frequent in the older age group, was the only independent factor associated with immunologic and clinical evolution of infection. Age >50 years was associated with earlier treatment discontinuation.
Received 16 February 2007; accepted 1 May 2007; electronically published 19 July 2007.
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Online publication date: 1-Dec-2008.
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