October 3, 2005
"Increased risk of incident HIV during pregnancy in Rakai, Uganda: a prospective study," Lancet: Ronald Gray of the Johns Hopkins Bloomberg School of Public Health and colleagues compared HIV incidence rates among sexually active pregnant and lactating women in Uganda to incidence among sexually active nonpregnant and nonlactating women. The researchers found that the risk of HIV infection during pregnancy increases. Hormonal changes affecting the genital tract or immune system, not changes in sexual behavior, likely are the cause of the increased risk, according to researchers. The researchers recommend targeted HIV prevention for pregnant women (Gray et al., Lancet, 10/1).
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