On 24 February 2011, FDA updated the nelfinavir (Viracept) label to include drug-drug interaction information between nelfinavir and wafarin.
Table 11 (Established and Other Potentially Significant Drug Interactions) of the Precautions section of the label was changed to add the following:
Coadministration of wafarin and nelfinavir may affect concentrations of wafarin. It is recommended that the INR (international normalised ratio) be monitored carefully during treatment with nelfinavir, especially when commencing therapy.
Please refer to the full label for details.
Source: FDA list serve (24 Feb 2011).
Viracept (nelfinavir) Label change reflects drug-drug interaction information with warfarin
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