March 1, 2011
Antabuse, a treatment for cocaine addiction and alcoholism, is now being examined as a possible tool to help eradicate HIV, report researchers from the University of California-San Francisco (UCSF) and Johns Hopkins University (JHU).
Twenty HIV-positive people are being sought for a study to assess whether Antabuse (disulfiram) is able to eliminate the remnants of leftover HIV that standard AIDS drugs cannot, according to information on the study at www.clinicaltrials.gov, a database kept by the National Institutes of Health. The trial is being led by UCSF Professor of Medicine Steven Deeks.
The study is rooted in yet-unpublished experiments on the outcome of Antabuse on dormant HIV by Robert Siliciano, a professor of medicine at JHU. While the drug is not expected to cure HIV/AIDS, it may provide a roadmap for future research, he said. "No single drug is likely to be able to eliminate these reservoirs," said Siliciano. "It's going to come down to some sort of combination of agents."
02.22.2011; Simeon Bennett
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