Two studies published in the New England Journal of Medicine "equip us with strategies to deal with the current imperfections in our scale-up efforts" to prevent mother-to-child transmission of HIV, write Marc Lallemant and Gonzague Jourdain of the Harvard School of Public Health in a New England Journal of Medicine editorial. The editorial compares the findings with updated WHO guidelines on PMTCT. The editorial also looks at questions that arise given the findings including: the difference in long-term response to the two drugs, strategies for preserving or "recycling" nevirapine therapy and the higher cost of ritonavir-boosted lopinavir compared with nevirapine (10/14).
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