May 22, 2008
HIV-positive people in the U.S., many of whom are living longer because of antiretroviral drugs, are at an increased risk for certain types of cancers, according to a study published Tuesday in the Annals of Internal Medicine, Reuters reports.
The study was conducted among 54,780 HIV-positive people and was based on cancer trends from 1992 to 2003. It found that as of 2003, anal cancer was 59 times more common among HIV-positive people than among the general population. In addition, Hodgkin's disease was 18 times more common among people living with HIV, followed by liver cancer at seven times more common, lung cancer at 3.6 times more common, skin cancer melanoma and throat cancer both at three times more common, and colorectal cancer at 2.4 times more common. Rates of Kaposi's sarcoma and non-Hodgkin lymphoma, which have typically been associated with HIV/AIDS, became relatively less common among people living with the disease, according to the study.
CDC's Pragna Patel, who led the study, said the most significant finding is the higher risk for anal cancer even in the "era" of highly active antiretroviral therapy. She added that multiple factors could explain the increased risk but that the risk might be linked to the spread of human papillomavirus, which is known to cause anal cancer, among men who have sex with men
Reprinted with permission from kaisernetwork.org. You can view the entire Kaiser Daily HIV/AIDS Report, search the archives, or sign up for email delivery at www.kaisernetwork.org/dailyreports/hiv. The Kaiser Daily HIV/AIDS Report is published for kaisernetwork.org, a free service of the Kaiser Family Foundation, by The Advisory Board Company. © 2008 by The Advisory Board Company and Kaiser Family Foundation. All rights reserved.